Evidence map›Paper›PMID 40439423›Full record

ArticleApplied and environmental microbiology2025

Harnessing flagellin of

Shunya Suzuki, Gregg A Dean, Akinobu Kajikawa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shunya SuzukiDepartment of Agricultural Chemistry, Tokyo University of Agriculture, Setagaya, Tokyo, Japan.ORCID 0000-0003-1964-7923
Gregg A DeanDepartment of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-7025-9550
Akinobu KajikawaDepartment of Agricultural Chemistry, Tokyo University of Agriculture, Setagaya, Tokyo, Japan.ORCID 0000-0002-2001-0551

Funding

Tokyo University of Agriculture
6 · The paper itself

Abstract

Lactic acid bacteria (LAB) are promising mucosal vaccine vectors due to their safety, immunostimulatory properties, and the availability of genetic tools for certain strains. Bacterial flagellin has attracted attention as both a versatile scaffold for antigen surface display and a potent adjuvant via Toll-like receptor 5 (TLR5) activation. Despite these advantages, LAB-derived flagellin remains largely unexplored as an antigen display platform. In this study, we demonstrate the potential of flagellin (FliC2) from

Indexed as

AIDS VaccinesEpitopesFlagellinHIV-1Adjuvants, ImmunologicAnimalsFemaleHumansMiceMice, Inbred BALB CToll-Like Receptor 5Adjuvants, ImmunologicAIDS VaccinesEpitopesFlagellinToll-Like Receptor 5flagellinlactic acid bacteriaLigilactobacillus agilismucosal vaccineTLR5

Identifiers

PMID40439423
PMCPMC12175526

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.