Evidence map›Paper›PMID 40439414›Full record

ArticleEmerging infectious diseases2025

Prospective Multicenter Surveillance of Non-H. pylori Helicobacter Infections during Medical Checkups, Japan.

Kengo Tokunaga, Emiko Rimbara, Toshihisa Tsukadaira, Katsuhiro Mabe, Koji Yahara, Hidekazu Suzuki, Tadashi Shimoyama, Mitsushige Sugimoto, Tadayoshi Okimoto, Hidenori Matsui and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Complete genome sequences of gastric non-Microbiology resource announcements · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kengo Tokunaga
Emiko Rimbara
Toshihisa Tsukadaira
Katsuhiro Mabe
Koji Yahara
Hidekazu Suzuki
Tadashi Shimoyama
Mitsushige Sugimoto
Tadayoshi Okimoto
Hidenori Matsui
Masato Suzuki
Keigo Shibayama
Hiroyoshi Ota
Kazunari Murakami
Mototsugu Kato

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate non-H. pylori Helicobacter (NHPH) infections in Japan, we enrolled 673 consecutive patients who underwent gastric endoscopy during annual medical checkups at 4 hospitals during April 2022-February 2023. We collected intragastric fluid and serum samples to detect NHPH infection by PCR and serologic tests. The prevalence of NHPH was 3% (20/673); 70% (14/20) of patients were infected with H. suis and 30% (6/20) with non-H. suis NHPH species. All 14 H. suis-infected patients were men and had a history of pork offal ingestion. Among non-H. suis NHPH-infected patients, 50% (3/6) owned pet cats, whereas only 22% (145/667) of other patients owned cats. Endoscopic evaluation revealed marbled crack-like gastritis was present in 93% (13/14) of H. suis-infected patients, a significantly higher prevalence than for H. pylori-infected (28.6%) and H. pylori eradication therapy (27.6%) groups. Pork offal ingestion and having pet cats increase risk for Helicobacter spp. infections.

Indexed as

HelicobacterHelicobacter InfectionsAdultAgedAged, 80 and overAnimalsCatsFemaleHelicobacter pyloriHumansJapanMaleMiddle AgedPetsPrevalenceProspective Studiesbacteriaenteric infectonsgastric diseasesgastric endoscopyHelicobacter infectionsHelicobacter pyloriHelicobacter suisJapanNHPHnon–Helicobacter pylori Helicobacter

Identifiers

PMID40439414
PMCPMC12123907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.