Evidence map›Paper›PMID 40439165›Full record

ReviewTurkish journal of ophthalmology2025

Ab Interno Goniotomy/Goniectomy Techniques

Zeynep Aktaş, Syril Dorairaj, Mohamed Sayed, Arsham Sheybani, Ahmet Yücel Üçgül, Isabella Wagner, Mohamed Khodeiry

Registry-linked trialAbstract readReview
In one paragraph

Review in Turkish journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07418853 (Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07418853 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries

TypeinterventionalSponsorHenry Ford Health SystemRan2026 to 2028Enrolled132ConditionsOpen Angle Glaucoma (OAG), Primary Open Angle Glaucoma (POAG), Secondary Open Angle GlaucomaArmsGoniotomy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zeynep AktaşUniversity of Texas Health, Department of Ophthalmology, San Antonio, TX, USAORCID 0000-0001-8339-3433
Syril DorairajMayo Clinic School of Medicine, Department of Ophthalmology, Jacksonville, FL, USAORCID 0000-0003-3251-4826
Mohamed SayedCleveland Clinic Abu Dhabi, Abu Dhabi, UAEORCID 0000-0001-5037-4754
Arsham SheybaniWashington University School of Medicine, Department of Ophthalmology and Visual Sciences, St Louis, MO, USAORCID 0000-0003-0137-4744
Ahmet Yücel ÜçgülKırşehir Ahi Evran University, Training and Research Hospital, Clinic of Ophthalmology, Kırşehir, TürkiyeORCID 0000-0001-9945-793X
Isabella WagnerMayo Clinic School of Medicine, Department of Ophthalmology, Jacksonville, FL, USA
Mohamed KhodeiryUniversity of Kentucky College of Medicine, Department of Ophthalmology and Visual Sciences, Lexington, KY; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAORCID 0000-0003-0109-5331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive glaucoma surgeries (MIGS), such as Kahook Dual Blade (KDB), bent ab interno needle goniectomy (BANG), gonioscopy-assisted transluminal trabeculotomy (GATT), OMNI, Trabectome, Streamline, and TrabEx+, have significantly advanced the treatment of glaucoma by improving aqueous humor outflow and reducing intraocular pressure (IOP). These innovative procedures target the trabecular meshwork (TM) and Schlemm’s canal, offering effective alternatives to more invasive filtration surgeries. By enhancing the natural drainage pathways, MIGS can achieve notable reductions in IOP and minimize the need for long-term glaucoma medications. Each device has a distinct mechanism of action. The KDB excises a strip of TM, while BANG uses a bent hypodermic needle for controlled goniectomy. GATT performs a 360-degree trabeculotomy using a microcatheter or Prolene (polypropylene) suture to open Schlemm’s canal. OMNI combines canaloplasty and trabeculotomy in a single procedure. The Trabectome ablates TM tissue with electrical energy, whereas Streamline performs viscodilation to expand outflow channels. TrabEx+ facilitates goniectomy with integrated irrigation and aspiration. Clinical studies have shown these MIGS techniques to be both safe and effective, with fewer complications compared to traditional surgeries like trabeculectomy or tube shunt implantation. MIGS procedures are particularly appealing due to their reduced recovery time and lower risk profile. However, further research is essential to establish their long-term efficacy and durability. Continued advancements and comprehensive long-term studies will ensure that MIGS provide sustainable and reliable benefits for glaucoma patients, optimizing treatment strategies in clinical practice.

Indexed as

GlaucomaGonioscopyIntraocular PressureMinimally Invasive Surgical ProceduresTrabecular MeshworkTrabeculectomyAqueous HumorHumansgoniectomygoniotomyMinimal invasive glaucoma surgery

Identifiers

PMID40439165
PMCPMC12192231

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.