SynthesisThe Journal of hand surgery, European volume2025
Prevalence of residual limb pain and neuromas after upper extremity amputation: a systematic review and meta-analysis.
Synthesis in The Journal of hand surgery, European volume, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of post-amputation pain in amputees: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Use of processed nerve allograft to relieve pain and restore function in individuals with painful upper limb neuroma-a case series of five individuals.Frontiers in surgery · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Residual limb pain (RLP) and symptomatic neuromas are common complications of upper extremity amputation. There is disagreement in the literature about their true prevalence. This systematic review and meta-analysis of the prevalence of RLP and symptomatic neuroma after upper extremity amputation identified relevant studies published between 2000 and 2022 in PubMed, Cochrane and Embase. Random-effects meta-analyses of proportions were performed to determine the prevalence of RLP and symptomatic neuromas. Subgroups were identified and analysed. For RLP, the pooled prevalence was 58% (95% CI: 46 to 68). For symptomatic neuromas, the pooled prevalence was 22% (95% CI: 11 to 40). Residual limb pain was reported less frequently in Europe than in the United States. Knowledge and awareness are important for appropriate treatment and prevention.
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Registered trials
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