ArticleOncology letters2025
Spinal cord metastasis in a long-term survivor of primary malignant glioblastoma: A case report.
Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
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Abstract
Glioblastoma (GBM) is the most common type of primary malignant brain tumor. Extracranial metastasis (ECM) is rare and usually indicates poor prognosis. We report a case of a 31-year-old female with GBM who underwent gross total resection followed by standard chemoradiotherapy. For recurrence, she received tumor treating fields and bevacizumab. At 23 months post-surgery, she developed COVID-19 pneumonia treated with dexamethasone, followed by spinal symptoms. MRI revealed L1-L2 lesions, and pathology after lumbar surgery confirmed ECM. Despite further treatment, the patient died of respiratory failure at 28 months. The present case illustrates the aggressive nature of ECM in GBM and the limited efficacy of current therapies in metastatic settings. Surgical resection and chemoradiotherapy remain the mainstay, while emerging treatments may provide hope for recurrent cases. Supportive care plays a critical role in advanced disease stages.
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