Evidence map›Paper›PMID 40438850›Full record

ArticleCureus2025

Advances in Molecular Imaging for the Early Detection and Management of Alzheimer's Disease.

Shiv A Goel, Rishab Singh, Deepa Regina John, Pokhraj Suthar, Jagadeesh S Singh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shiv A GoelDepartment of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.
Rishab SinghDepartment of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.
Deepa Regina JohnRadiology, East Suffolk and North Essex Trust NHS, Colchester, GBR.
Pokhraj SutharDepartment of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.
Jagadeesh S SinghDepartment of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by impairments in memory and cognitive abilities. The development of new immunotherapies targeting beta-amyloid (Aβ) and tau protein deposition in the brain is ushering in great advances in clinical management. Advances in molecular imaging techniques, particularly positron emission tomography (PET) with amyloid and tau tracers, have facilitated the early detection of Alzheimer's pathology. We report a case of a 67-year-old patient presenting with mild cognitive impairment (MCI) who was confirmed to have AD on newer PET imaging. This report highlights the important role of molecular imaging in the early diagnosis of AD before significant clinical and functional decline sets in, thereby emphasizing its role in clinical practice.

Indexed as

alzheimer’s diseaseamyloid petearly detectionmild cognitive impairmentmolecular imagingtau pet

Identifiers

PMID40438850
PMCPMC12118448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.