Evidence map›Paper›PMID 40438717›Full record

ArticleWorld journal of gastrointestinal endoscopy2025

Colon capsule endoscopy is an effective filter test for colonic polyp surveillance.

Serhiy Semenov, Mohd Syafiq Ismail, Sandeep Sihag, Thilagaraj Manoharan, Phyllis Reilly, Gerard Boran, Barbara Ryan, Niall Breslin, Anthony O'Connor, Sarah O'Donnell and 1 more

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Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Serhiy SemenovTrinity Academic Gastroenterology Group, School of Medicine - Trinity College Dublin, Dublin D2, Ireland.
Mohd Syafiq IsmailTrinity Academic Gastroenterology Group, School of Medicine - Trinity College Dublin, Dublin D2, Ireland.
Sandeep SihagTrinity Academic Gastroenterology Group, School of Medicine - Trinity College Dublin, Dublin D2, Ireland.
Thilagaraj ManoharanDepartment of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland.
Phyllis ReillyDepartment of Clinical Chemistry, Tallaght University Hospital, Dublin D24, Ireland.
Gerard BoranDepartment of Clinical Chemistry, Tallaght University Hospital, Dublin D24, Ireland.
Barbara RyanDepartment of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland.
Niall BreslinDepartment of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland.
Anthony O'ConnorDepartment of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland.
Sarah O'DonnellDepartment of Gastroenterology, Tallaght University Hospital, Dublin D24, Ireland.
Deirdre McNamaraTrinity Academic Gastroenterology Group, School of Medicine - Trinity College Dublin, Dublin D2, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurveillance colonoscopies are predominantly normal, identifying patients for potential polypectomy is advantageous.

aimTo assess colon capsule endoscopy (CCE) and/or faecal immunochemical test (FIT) as filters in surveillance.

methodsPatients aged ≥ 18 due for polyp surveillance were invited for CCE and FIT. Identifying polyps or colorectal cancer resulted in a positive CCE. Significant lesions (≥ 3 polyps or ≥ 6 mm polyps), incomplete studies and positive FITs (≥ 225 ng/mL) were referred for endoscopy. CCE and endoscopy results, FIT accuracy and patient preference were assessed.

resultsFrom a total of 126 CCEs [mean age 64 (31-80), 67 (53.2%) males), 70.6% (89/126) were excreted, 86.5% (109/126) had adequate image quality. CCE positivity was 70.6% (89/126), 42.9% (54/126) having significant polyps with 63.5% (80/126) referred for endoscopy (19 sigmoidoscopies, 61 colonoscopies). CCE reduced endoscopy need by 36.5% (46/126) and 51.6% (65/126) were spared a colonoscopy. CCE positive predictive value was 88.2% (45/51). Significant extracolonic findings were reported in 3.2% (4/126). Patients with positive CCEs were older > 65 [odds ratio (OR) = 2.5, 95% confidence interval (CI): 1.1517-5.5787,

conclusionCCE appears effective in low-risk polyp surveillance. FIT does not appear to be of benefit in surveillance.

Indexed as

Capsule endoscopyColon capsule endoscopyColonic polypFaecal immunochemical testPolyp surveillance

Identifiers

PMID40438717
PMCPMC12110150

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