Evidence map›Paper›PMID 40438677›Full record

ArticleFrontiers in oncology2025

Hyperleukocytosis, leukemoid reaction caused by malignant peritoneal mesothelioma: a case report and review of literature.

Kaibo Zhu, Dan Zhou, Kang Liu, Lingzhen Wu, Juan Jin, Zimian Luo

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaibo ZhuDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.
Dan ZhouDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.
Kang LiuDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.
Lingzhen WuDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.
Juan JinDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.
Zimian LuoDepartment of Hematology, Xiangtan Central Hospital, Xiangtan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic leukemoid reaction (PLR)-induced hyperleukocytosis remains a critical diagnostic challenge. Malignant peritoneal mesothelioma, known for its nonspecific clinical presentation, often evades early detection. We report a 75-year-old male with cirrhosis presenting with fever (38.2°C), progressive ascites, leukocytosis (109.9×10

Indexed as

cytokineglucocorticoidshyperleukocytosismalignant peritoneal mesotheliomaparaneoplastic leukemoid reaction

Identifiers

PMID40438677
PMCPMC12116308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.