Evidence map›Paper›PMID 40438488›Full record

ArticleActa medica Philippina2025

Determination of Toxicity and Hypoglycemic Effect in Alloxan-induced Diabetic Mice of

Carmina Mae S Bautista, Bryan M Amante, Edwin C Ruamero

Abstract read
In one paragraph

Article in Acta medica Philippina, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carmina Mae S BautistaCollege of Pharmacy, University of the Philippines Manila.
Bryan M AmanteCollege of Pharmacy, University of the Philippines Manila.
Edwin C RuameroCollege of Pharmacy, University of the Philippines Manila.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: The cytotoxicity assay was necessary to screen which extract and fractions will be used for the Results: The hypoglycemic activity was examined in alloxan-induced diabetic mice using Conclusion: The effectiveness of aqueous crude extract in reduction of blood glucose in mice may be attributed to the synergistic effects of phytochemicals present, especially the alkaloids which were retained in the extract but were undetectable in the fractionated samples. The results of this study also support the findings of existing ethnopharmacological studies on

Indexed as

alkaloidsAlloxan-induced miceblood glucose reductionethnopharmacologyHepG2HK-2hypoglycemic agentNon-Radioactive Cytotoxicity Assaysynergistic effects

Identifiers

PMID40438488
PMCPMC12106103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.