ArticleInternational journal of women's health2025
UDP-Glucose Ceramide Glucosyltransferase Inhibition, Immune Cell Mediation, and Endometriosis Risk: A Mendelian Randomization Study.
Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Targeting the Immune Network in Endometriosis: A Comprehensive Review of Pathogenesis, Immunomodulation, and Emerging Therapies.Pharmaceuticals (Basel, Switzerland) · 2026Review
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Authors and funding
5 authors.
Funding
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Abstract
Purpose: Previous studies have reported a link between UDP-glucose ceramide glucosyltransferase (UGCG), immune regulation, and endometriosis (EM). We hypothesized that UGCG inhibitors might exert therapeutic effects on EM. Therefore, in this study, we performed a two-sample, two-step Mendelian randomization (MR) analysis modeling genetic variation of UGCG inhibitors to investigate the causal relationship between genetically determined Methods: Two-sample MR was conducted using genome-wide association study data on Results: Conclusion: Inhibiting UGCG activity may reduce the risk of EM, and immune cells may mediate this effect. Our findings provide novel insights for the development of potential therapeutic strategies for EM treatment.
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