ArticleEthiopian journal of health sciences2024
Keratinizing Pleomorphic Adenoma of the Buccal Mucosa: A Comprehensive Clinical and Histopathological Analysis of a Rare Case.
Article in Ethiopian journal of health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Salivary gland tumors make up a relatively small proportion, ranging from 1% to 4%, of all neoplasms in the human body. Among these, pleomorphic adenoma stands out as a distinct benign tumor of the salivary glands, characterized by a combination of epithelial and mesenchymal elements.Only 0.3% to 1.5%, of biopsies in oral and Maxillofacial pathology laboratories are associated with tumors originating from minor salivary glands. Keratinizing pleomorphic adenoma, a rare variant accounting for 5-10% of all pleomorphic adenomas, differs from the typical form due to the presence of keratin within the tumor cells, serving as a distinguishing histological feature. The incidence of keratinizing pleomorphic adenoma is not well-established but is believed to be less than 1 case per 100,000 people per year. Here we present an atypical histopathological variation of pleomorphic adenoma, featuring extensive keratinization and manifesting in a less typical anatomical location in a 57-year-old male patient.
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