Evidence map›Paper›PMID 40438423›Full record

ArticleEuropean heart journal. Case reports2025

Running into trouble: exercise-exacerbated recurrent pericarditis-a case report.

Tess Calcagno, Jibran Ikram, Felix Berglund, Allan Klein

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tess CalcagnoDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, 3566 Grosvenor Rd, Cleveland Heights, OH 44118, USA.ORCID https://orcid.org/0000-0002-4087-3901
Jibran IkramDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, 3566 Grosvenor Rd, Cleveland Heights, OH 44118, USA.
Felix BerglundDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, 3566 Grosvenor Rd, Cleveland Heights, OH 44118, USA.
Allan KleinDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, 3566 Grosvenor Rd, Cleveland Heights, OH 44118, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recurrent pericarditis is an inflammatory condition characterized by symptom recurrence after an initial episode. Exercise-induced flares are underrecognized. Case Summary: A 53-year-old male presented with recurrent pericarditis, initially diagnosed in June 2020 and inadequately treated with a three-month colchicine course. He experienced four exercise-induced flares coinciding with triathlon training, each resolving spontaneously. In August 2024, the patient presented with severe right shoulder pain and tachycardia. Diagnostic evaluation revealed a moderate pericardial effusion, prompting a pericardial window. Despite colchicine and NSAIDs, symptoms recurred, and MRI confirmed active pericarditis with late gadolinium enhancement of the pericardium. Given the refractory nature of his disease, biologic therapy with rilonacept was initiated. Discussion: This case highlights the association between high-intensity exercise and recurrent pericarditis, underscoring the need for individualized treatment strategies, including biologics. It contributes to the understanding of refractory cases and exercise-induced inflammation.

Indexed as

BiologicsCardiac MRICase reportExerciseImagingInflammationLGEPericarditis

Identifiers

PMID40438423
PMCPMC12117366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.