Evidence map›Paper›PMID 40438267›Full record

ArticleBeilstein journal of nanotechnology2025

Colloidal few layered graphene-tannic acid preserves the biocompatibility of periodontal ligament cells.

Teissir Ben Ammar, Naji Kharouf, Dominique Vautier, Housseinou Ba, Nivedita Sudheer, Philippe Lavalle, Vincent Ball

Abstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teissir Ben AmmarINSERM UMR_S 1121, CNRS EMR 7003, Université de Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, 1 rue Eugène Boeckel, Strasbourg F-67000, France.ORCID https://orcid.org/0009-0003-3645-2690
Naji KharoufINSERM UMR_S 1121, CNRS EMR 7003, Université de Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, 1 rue Eugène Boeckel, Strasbourg F-67000, France.
Dominique VautierINSERM UMR_S 1121, CNRS EMR 7003, Université de Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, 1 rue Eugène Boeckel, Strasbourg F-67000, France.
Housseinou BaBlackleaf, Illkirch-Graffenstaden, 67400, France.
Nivedita SudheerInstitut de physique et chimie des Matériaux de Strasbourg (IPCMS), Centre National de la Recherche Scientifique UMR 7504, 23 rue du Loess, 67034 Strasbourg Cedex 2 BP43, France.
Philippe LavalleINSERM UMR_S 1121, CNRS EMR 7003, Université de Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, 1 rue Eugène Boeckel, Strasbourg F-67000, France.
Vincent BallINSERM UMR_S 1121, CNRS EMR 7003, Université de Strasbourg, Biomaterials and Bioengineering, Centre de Recherche en Biomédecine de Strasbourg, 1 rue Eugène Boeckel, Strasbourg F-67000, France.ORCID https://orcid.org/0000-0002-7432-4222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental diseases pose a global health concern. In addition to medication and care, the use of biocompatible and even bioactive dental materials can contribute to global oral health. Among such materials, nanomaterials begin to be used. In this context, the incorporation of graphene-based materials into dental biomaterials could offer advantages such as increased mechanical strength. Nevertheless, biocompatibility issues still hinder their adoption. In this study, a biocomposite of few-layered graphene and tannic acid (FLG-TA) was synthesized through a straightforward, bio-based methodology. Physicochemical characterizations elucidated the structural and morphological attributes of the biocomposite. By incorporating antioxidant TA molecules onto the FLG surface, the biocomposite dynamically mitigated reactive oxygen species, demonstrating no cytotoxicity to periodontal ligament cells up to 200 µg·mL

Indexed as

antioxidant propertiesbiocompatibilitydental applicationsfew layered graphene–tannic acid biocomposite (FLG–TA)periodontal ligament cells (PDL)

Identifiers

PMID40438267
PMCPMC12117215

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.