Evidence map›Paper›PMID 40438140›Full record

ArticleClinical neuroimaging (Hoboken, N.J.)2025

Novel Mammillary Body Manual Segmentation: Application for Quantitative MRI Analysis of Critically Ill Infants.

Mackenzie S Kagan, David Zurakowski, Emi Takahashi, Russell W Jennings, Dusica Bajic

Abstract read
In one paragraph

Article in Clinical neuroimaging (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mackenzie S KaganDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-6547-2373
David ZurakowskiDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-3610-6942
Emi TakahashiHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-9820-3356
Russell W JenningsHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-0133-2707
Dusica BajicDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-3943-2105

Funding

Immediate and Delayed Effects of Morphine on Brain Circuits: Animal and Human CorK08DA035972 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI BAJIC, DUSICA · 2013 to 2017
$928k
Impact of Prolonged Perioperative Sedation on Infant BrainR21DA058072 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI BAJIC, DUSICA · 2023 to 2024
$502k
NIDA NIH HHS K08 DA035972NIDA NIH HHS R21 DA058072
6 · The paper itself

Abstract

Background and Purpose: Previous qualitative studies have shown that mammillary body (MB) assessment can serve as an early marker of poor long-term neurodevelopmental outcomes. This study aims to establish a reliable quantitative method for analyzing the surface area, volume, and signal intensity of MB in infancy. Methods: A novel methodology was retrospectively tested in a cohort of critically ill preterm and term-born patients following Results: High Conclusions: This novel study describes efficient and accurate MB masking and quantification, supporting MB as a potential early marker. However, the negative results presented in infants born with

Indexed as

braincritical illnessEAesophageal atresiaoesophageal atresiaprematureterm-born

Identifiers

PMID40438140
PMCPMC12118771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.