Evidence map›Paper›PMID 40437958›Full record

ArticleActa biochimica et biophysica Sinica2025

Andrographolide prevents necroptosis by suppressing the generation of reactive oxygen species.

Na Lu, Qing Li, Linghan Duan, Rong Xu, Yaping Li, Fuli Shi, Zhiya Zhou, Yingqing Gan, Bo Hu, Jinhua Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Na LuGuangdong Provincial Key Laboratory of Spine and Spinal Cord Reconstruction, the Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China.
Qing LiGuangdong Provincial Key Laboratory of Spine and Spinal Cord Reconstruction, the Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China.
Linghan DuanDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Rong XuDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Yaping LiDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Fuli ShiDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Zhiya ZhouDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Yingqing GanDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Bo HuDepartment of Nephrology, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Jinhua LiDepartment of Ultrasound, the Fifth Affiliated Hospital of Jinan University (Heyuan Shenhe People's Hospital), Heyuan 517000, China.
Xianhui HeGuangdong Provincial Key Laboratory of Spine and Spinal Cord Reconstruction, the Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China.
Dongyun OuyangDepartment of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Qingbing ZhaGuangdong Provincial Key Laboratory of Spine and Spinal Cord Reconstruction, the Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Andrographolide (Andro), a natural product extracted from the Chinese traditional medicine herb

Indexed as

andrographolidemitochondrianecroptosisnecrosomeNrf2reactive oxygen species

Identifiers

PMID40437958
PMCPMC12747933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.