ArticleJournal of fish diseases2025
Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach.
Article in Journal of fish diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Omics technologies in aquafeed: unlocking the black box towards systems biology.Functional & integrative genomics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV). The resulting cardiomyopathies impact fish stock in terms of mortality, quality, growth performance and economic loss. Diagnosis of these diseases is currently based on clinical signs, histopathology and RT-qPCR. To identify putative biomarkers for use in the health assessment of Atlantic salmon, a quantitative proteomics investigation was undertaken with the aim of differentiating fish with CMS from healthy fish and fish with PD. Serum samples (n = 9/group) were collected during health assessment from pens where clinical CMS or PD were present and compared to serum from healthy Atlantic salmon. There were 34 differentially abundant proteins (DAPs) in CMS compared to healthy, 66 comparing CMS to PD, and 81 comparing PD to healthy. In relation to healthy samples, most DAPs were shared between CMS and PD, with higher relative abundances observed in PD. An exception to this was serum fibrinogen, which was identified as a putative biomarker for CMS, whereas differentiation of Atlantic salmon with CMS from those with PD was enhanced by the calculation of the ratio of fibrinogen to skeletal troponin C.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.