Evidence map›Paper›PMID 40437628›Full record

ArticleGeneral thoracic and cardiovascular surgery cases2025

Totally endoscopic mitral valve repair and papillary muscle ablation for arrhythmic mitral regurgitation.

Naoki Murata, Daisuke Endo, Hidemori Hayashi, Minoru Tabata

Abstract read
In one paragraph

Article in General thoracic and cardiovascular surgery cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mitral Valve Surgery with and Without Mitral Annular Disjunction: A Meta-Analysis.Journal of cardiovascular development and disease · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Naoki MurataDepartment of Cardiovascular Surgery, Juntendo University School of Medicine, 2-2-1, Hongo, Bunkyo, Tokyo, 113-8431, Japan.
Daisuke EndoDepartment of Cardiovascular Surgery, Juntendo University School of Medicine, 2-2-1, Hongo, Bunkyo, Tokyo, 113-8431, Japan.
Hidemori HayashiDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine, 2-2-1, Hongo, 113-8431, Bunkyo, Tokyo, Japan.
Minoru TabataDepartment of Cardiovascular Surgery, Juntendo University School of Medicine, 2-2-1, Hongo, Bunkyo, Tokyo, 113-8431, Japan. minorutabata@juntendo.ac.jp.ORCID http://orcid.org/0000-0002-8718-0088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArrhythmic mitral regurgitation (MR), characterized by mitral valve prolapse accompanied by ventricular arrhythmias, poses diagnostic and therapeutic challenges. Treatment decisions, including the necessity for concomitant surgical ablation and the identification of specific ablation points, are highly case-specific and lack a consensus approach. Once determined, high-definition endoscopes and adaptable cryoablation tools facilitate simultaneous mitral valve repair and targeted surgical ablation via a minimally invasive approach, ensuring optimal visualization. CASE PRESENTATION: The patient was a 49-year-old female with an episode of ventricular fibrillation. Severe MR was diagnosed at that time; however, surgery was not selected due to the absence of symptoms and left ventricular dysfunction. An implantable cardioverter-defibrillator was subsequently placed, which activated twice. Over the last 6 months, she developed dyspnea and was referred to us, where she was diagnosed with symptomatic arrhythmic MR. Subsequently, she underwent totally endoscopic minimally invasive mitral valve repair and papillary muscle cryoablation. Postoperative echocardiography showed trivial MR, with a mean pressure gradient of 1 mmHg, and an ejection fraction of 56%. She was discharged home on the fifth postoperative day. The Holter electrocardiogram performed 6 months after surgery showed no ventricular arrhythmias originating from the papillary muscles.

conclusionsWe successfully diagnosed and treated a patient with symptomatic arrhythmic MR. Simultaneous mitral valve repair and papillary muscle cryoablation, performed through a totally endoscopic minimally invasive approach, was found to be effective in managing this complex condition.

Indexed as

Arrhythmic mitral regurgitationCryoablationMinimally invasive surgeryMitral regurgitation

Identifiers

PMID40437628
PMCPMC12121146

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.