Evidence map›Paper›PMID 40437530›Full record

ArticleBMC oral health2025

Rural Pakistan's smokeless tobacco epidemic: a need for tailored interventions.

Ziaur Rahman Khan, Syed Jaffar Abbas Zaidi, Sania Riaz, Usman Mahboob, Sana Mirza, Fizza Khalid, Ushnah Imran

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ziaur Rahman KhanDepartment of Oral Medicine, Baqai Dental College, Baqai Medical University, Karachi, Pakistan. drziakhan@hotmail.com.
Syed Jaffar Abbas ZaidiDepartment of Oral Biology and Digital Learning Centre, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan.
Sania RiazDepartment of Periodontology, Baqai Dental College, Baqai Medical University, Karachi, Pakistan.
Usman MahboobInstitute of Health Professions Education and Research, Khyber Medical University, Peshawar, Pakistan.
Sana MirzaDepartment of Oral Pathology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Fizza KhalidDepartment of Periodontology, Baqai Dental College, Baqai Medical University, Karachi, Pakistan.
Ushnah ImranDepartment of Oral Medicine, Baqai Dental College, Baqai Medical University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral cancer is a leading cause of death in Pakistan, with a significant burden among rural populations. The primary risk factor for oral cancer in this region is the widespread use of smokeless tobacco (SLT). Despite international efforts to reduce tobacco consumption, SLT use remains prevalent. This study aimed to explore the experiences of a rural population with SLT use.

methodsThis qualitative study employed an exploratory, phenomenological approach in Gadap Town, a rural area near Karachi, to investigate how local socioeconomic realities and cultural norms influence SLT use. The interview transcripts of 28 SLT users (75% men, 25% women), purposively sampled, were included in the final analysis. Transcripts were thematically analysed after verbatim transcription and translation.

resultsFour major themes emerged: (1) Dynamics of addiction, including peer influence, familial patterns, and stress-related coping; (2) Risk perception, spanning awareness of oral cancer risk yet persistent usage; (3) Cessation journey, highlighting withdrawal challenges, emotional dependency, and limited professional support; and (4) Socioeconomic factors, notably the economic burden on households and calls for stricter regulation. Although participants recognized health hazards, they found cessation difficult due to emotional reliance and minimal external assistance. Socioeconomic factors, including the increased availability of unregulated, untaxed SLT products and limited free access to cessation support, were identified as critical influences. Participants emphasized the potential role of strict regulatory measures and relevant interventions in supporting cessation.

conclusionThis study highlights a critical disconnect between participants' awareness of the harmful effects of SLT and their actual behaviour in attempting cessation. Despite being aware of the health risks, such as oral cancer, participants often continued SLT use due to emotional dependency and socioeconomic factors. Interventions that focus on culturally relevant cessation strategies, stress and financial management, and strict regulatory enforcement are essential to bridge this gap to support behavioural change. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

EpidemicsRural PopulationTobacco, SmokelessAdaptation, PsychologicalAdultFemaleHumansMaleMiddle AgedMouth NeoplasmsPakistanPeer InfluenceQualitative ResearchRisk FactorsSocioeconomic FactorsTobacco Use CessationCessationOral cancerRural PakistanSmokeless tobaccoSocioeconomic factors

Identifiers

PMID40437530
PMCPMC12117969

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.