Evidence map›Paper›PMID 40437487›Full record

ArticleBMC veterinary research2025

First study to describe the prevalence and epidemiology of African swine fever, classical swine fever, porcine reproductive and respiratory syndrome and swine flu in Kazakhstan.

Yuliya V Perfilyeva, Elina R Maltseva, Yekaterina O Ostapchuk, Andrey V Zhigailov, Anna S Nizkorodova, Alena S Cherusheva, Dinara A Naizabayeva, Zhanna A Berdygulova, Akerke O Bissenbay, Tatyana V Kuznetsova and 7 more

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuliya V PerfilyevaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Elina R MaltsevaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Yekaterina O OstapchukAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Andrey V ZhigailovAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Anna S NizkorodovaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Alena S CherushevaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Dinara A NaizabayevaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Zhanna A BerdygulovaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Akerke O BissenbayAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Tatyana V KuznetsovaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Saltanat A KuatbekovaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Gulnara A IsmagulovaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Andrey M DmitrovskiyAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Dong-Hun LeeWildlife/One Health Lab, College of Veterinary Medicine, Konkuk University, Seoul, South Korea.
Seidigapbar M MamadaliyevAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Yuriy A SkibaAlmaty Branch of the National Center for Biotechnology, 14 Zhahanger St., Almaty, 050054, Kazakhstan.
Guillermo R RisattiDepartment of Pathobiology and Veterinary Science, Connecticut Veterinary Medical Diagnostic Laboratory, College of Agriculture, Health and Natural Resources, University of Connecticut, 61 N. Eagleville Road, Unit 3089, Storrs, CT, 06269-3089, USA. guillermo.risatti@uconn.edu.

Funding

Ministry of Science and Higher Education of the Republic of Kazakhstan BR24992948US Defense Threat Reduction Agency KZ-35
6 · The paper itself

Abstract

backgroundKazakhstan, the ninth-largest country in the world, located in Central Asia and bordering China, Kyrgyzstan, Russia, Turkmenistan, and Uzbekistan, hosts a diverse population of domestic pigs across various environments, providing potential hosts for highly pathogenic viral diseases of swine. Here we monitored African Swine Fever Virus (ASFV), Classical Swine Fever Virus (CSFV), Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and Swine Influenza Virus (SIV).

resultsDuring the spring and fall of 2019, we sampled 1,459 domestic pigs in northern, central and eastern Kazakhstan. Samples were tested for antibodies by ELISA and for viral genomes by qPCR and RT-qPCR. No antibodies against ASFV or ASFV DNA were detected in sampled animals. Of the 84 farms sampled, 16.6% had at least one animal vaccinated against CSF. Seropositive pigs were found on a farm in Oskemen with no history of vaccination against CSFV. No CSFV RNA was detected in the blood of the sampled animals. Only 12.2% of the animals tested were vaccinated against PRRS with live-attenuated vaccines. The true animal-level seroprevalence of PRRS on unvaccinated farms was 16.6%. PRRSV RNA was detected in 17 unvaccinated animals in Pavlodar oblast on farms that were vaccinated against PRRS. The identified PRRSV-1 strains belonged to subtype 1 and clustered with the PRRS DV vaccine virus strain. A large proportion of the pigs had antibodies against SIV, with true animal-level seroprevalence of 35.9% and herd-level seroprevalence of 23.2%. Antibodies against the influenza A viruses of hemagglutinin subtypes H1 and H3 were found in the examined pigs. None of the animals were vaccinated against SIV. The variable 'commercial farming' showed an association with PRRSV and IAV seroprevalence. Of the unvaccinated farms, 9% were co-infected with PRRSV and SIV.

conclusionsResults confirm the domestic pig population in Kazakhstan was not infected with ASFV but indicated exposure to PRRSV and SIV. This underscores the need for monitoring these infections in the region to manage their impact.

Indexed as

African Swine FeverClassical Swine FeverOrthomyxoviridae InfectionsPorcine Reproductive and Respiratory SyndromeSwine DiseasesAfrican Swine Fever VirusAnimalsAntibodies, ViralKazakhstanPorcine respiratory and reproductive syndrome virusPrevalenceSeroepidemiologic StudiesSwineAntibodies, ViralAfrican Swine FeverClassical Swine FeverKazakhstanPorcine Reproductive and Respiratory SyndromeSwine Influenza

Identifiers

PMID40437487
PMCPMC12117688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.