Evidence map›Paper›PMID 40437380›Full record

ArticleBMC geriatrics2025

Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components.

Ling Xu, Zhefeng He, Chao Fu, Yiyang Wu, Anwei Wu, Guojiang Tian, Jianfei Huang, Xibo Liu, Qi Wang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ling XuDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Zhefeng HeDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Chao FuDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Yiyang WuDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Anwei WuDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Guojiang TianDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Jianfei HuangDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Xibo LiuDepartment of Pathology, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Qi WangDepartment of Colorectal Surgery, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China. wangqi0601@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSignet ring cell carcinoma is a rare histological type among the various forms of colorectal cancers. Even rare is when it coexisted with neuroendocrine components in one tumor. To date, there is little literature reported case of colorectal cancer diagnosed as signet ring cell carcinoma with neuroendocrine components. CASE PRESENTATION: This report presents a unique case manifested as obstructed defecation for more than one month but with negative endoscopic biopsies. Laparoscopic abdominoperineal resection was performed. Based on the postoperative pathology, the patient was finally diagnosed as signet ring cell carcinoma with neuroendocrine differentiation among poorly differentiated adenocarcinoma. DISCUSSION AND

conclusionsWe highlight the rare coexistence of signet ring cell carcinoma and neuroendocrine differentiation in this case. We also emphasize the special characteristic of intramural growth without penetrating the mucosa in signet ring cell carcinoma, further to pose the pitfalls and share lessons during our diagnosis and treatment process.

Indexed as

Carcinoma, Signet Ring CellRectal NeoplasmsHumansBiopsyLaparoscopic abdominoperineal resectionLow rectal cancerNeuroendocrine differentiationSignet ring cell carcinoma

Identifiers

PMID40437380
PMCPMC12117679

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.