Evidence map›Paper›PMID 40437344›Full record

ArticleClinical and translational allergy2025

Association between telomere length and atopic dermatitis among school-age children.

Hsin-Yi Huang, Kun-Hua Sheen, Chi-Yen Hung, Ju Chang-Chien, Shih-Ling Wang, Chia-Hua Ho, Hui-Ju Tsai, Tsung-Chieh Yao

Abstract read
In one paragraph

Article in Clinical and translational allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hsin-Yi HuangDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID https://orcid.org/0009-0003-2254-9598
Kun-Hua SheenDepartment of Medical Science, National Tsing Hua University, Hsinchu, Taiwan.
Chi-Yen HungDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ju Chang-ChienDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Shih-Ling WangDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chia-Hua HoDepartment of Family Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Hui-Ju TsaiDepartment of Medical Science, National Tsing Hua University, Hsinchu, Taiwan.ORCID https://orcid.org/0000-0002-5338-6117
Tsung-Chieh YaoDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0002-5457-1402

Funding

Chang Gung Medical Foundation CMRP3N0371∼3Chang Gung Medical Foundation CMRPG3J0121∼3Chang Gung Medical Foundation CMRPG3J1711∼2Chang Gung Medical Foundation CMRPG3M1831∼3National Science and Technology Council, Taiwan MOST 109-2314-B-182-042-MY3National Science and Technology Council, Taiwan NSTC 111-2314-B-400-040-MY3National Science and Technology Council, Taiwan NSTC 112-2314-B-182-030-MY3
6 · The paper itself

Abstract

backgroundAtopic dermatitis is a common chronic skin disease in children. Whether telomere length is associated with atopic dermatitis remains unclear. This population-based case-control study aimed to investigate the association between telomere length and atopic dermatitis in school-age children.

methodsIn this cross-sectional analysis, we included 1084 singleton term-born children (608 males; mean age 6.4 years) from the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren cohort. Telomere length was measured using quantitative real-time polymerase chain reaction, log-transformed and was analyzed in quartiles. The main outcome was atopic dermatitis defined as having physician-diagnosed atopic dermatitis and the presence of atopic dermatitis in the last 12 months. Regression analyses were used to assess the relationship between telomere length and atopic dermatitis.

resultsTelomere length was significantly inversely associated with childhood atopic dermatitis after adjusting for child's age, sex, overweight or obesity, birth season, childhood allergic diseases, environmental tobacco smoke, parental history of allergic diseases, parental educational level, and breastfeeding status (p_

conclusionThis study provides new evidence suggesting an association between shorter telomere length and atopic dermatitis in school-age children.

Indexed as

atopic dermatitischildrentelomere length

Identifiers

PMID40437344
PMCPMC12119238

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.