ArticleGeneral thoracic and cardiovascular surgery2025
Vagus nerve/recurrent laryngeal nerve ratio: proposal of a new parameter predicting left vocal cord palsy using intraoperative nerve monitoring during esophagectomy.
Article in General thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimIntraoperative nerve monitoring (IONM) during esophageal cancer surgery can help to identify and preserve the recurrent laryngeal nerve (RLN). To devise a useful parameter for prediction of left vocal cord palsy (VCP), we measured the electromyographic (EMG) amplitude of the left RLN and vagus nerve (VN) using intermittent IONM.
methodsWe studied 35 consecutive patients who underwent esophagectomy with lymph node dissection around the left RLN. After lymph node dissection, the left RLN and left VN were stimulated, and the EMG amplitude was measured using IONM. The VN/RLN ratio (V/R ratio) was calculated, and the presence of left VCP, diagnosed by laryngoscopy on the first postoperative day, was compared among the patients.
resultsTen of the 35 patients (28.6%) had left VCP. In the VCP and non-VCP groups, the left VN amplitude was 190.0 (0-1111) µV and 520.0 (120-1200) µV (P = 0.006), and the VR ratio was 0.26 (0-0.75) and 0.71 (0.24-1.0) (P < 0.001), respectively. Receiver operating characteristic curve analysis using the left VN amplitude and V/R ratio showed an area under the curve (AUC) of 0.80 with a cutoff of 354 µV, and an AUC 0.90 with a cutoff of 0.50, respectively(P = 0.05). When left VN amplitudes of < 100 μV, < 354 μV, and a V/R ratio of ≤ 0.50 were defined as left VCP, the accuracy was 80.0%, 74.2%, and 88.6%, respectively.
conclusionsUsing intermittent IONM, the V/R ratio with a cutoff value of 0.50 has the potential to be a more useful parameter for prediction of VCP after esophagectomy than EMG amplitude during VN stimulation.
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