ArticleCommunications medicine2025
A multinational cohort study of trends in survival following dementia diagnosis.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
- Outcome-specific risk factors challenge universal dementia prevention priorities: Findings from the Egyptian Dementia Network Registry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Trends in Dementia Incidence, Prevalence, and Mortality among Older Hong Kong Chinese, 2005-2019: A Population-Based Study.Neuroepidemiology · 2026Article
- Clinical and Medication Factors Associated with Cognitive Decline in Dementia: A Healthcare Database Study.Current Alzheimer research · 2026Article
- Dementia's mortality in America: a local, regional, and temporal evaluation.Dementia & neuropsychologia · 2026Article
- Article
- Prescribing trends and time series analysis of blood pressure-lowering drugs among patients with dementia: a multinational database study.EClinicalMedicine · 2025Article
- Comprehensive descriptive analysis of large Alzheimer's disease patient cohorts.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abatract
backgroundInformation on the survival of people living with dementia over time and across systems can help policymakers understand the real-world impact of dementia on health and social care systems. This multinational cohort study examines the trends in relative mortality risk following a dementia diagnosis.
methodsA common protocol was applied to population-based data from the UK, Germany, Finland, Canada (Ontario), New Zealand, South Korea, Taiwan and Hong Kong. Individuals aged 60+ with an incident dementia diagnosis recorded between 2000 and 2018 were followed until death or the end of the study period. Cox proportional hazards regression was used to assess the association of mortality in dementia patients with the year of dementia diagnosis.
resultsData from 1,272,495 individuals, with the mean age at diagnosis ranging from 76.8 years (South Korea) to 82.9 years (Germany), show that the overall median length of survival following recorded diagnosis ranges from 2.4 years (New Zealand) to 7.9 years (South Korea). Hazard ratios (HRs) estimated from Cox proportional hazard models decline consistently over the study period in the UK, Canada, South Korea, Taiwan and Hong Kong, which accounted for 84% of all participants. For example, the HR decreases from 0.97 (95% CI: 0.92-1.02) in 2001 to 0.72 (0.65-0.79) in 2016 in comparison to year 2000 in the UK.
conclusionsThis study shows a steady trend of decreasing risk of mortality in five out of eight databases, which signals the potential positive effect of dementia plans and associated policies and provides reference for future policy evaluation.
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Registered trials
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