Evidence map›Paper›PMID 40437095›Full record

ArticleNature2025

Astrocyte morphogenesis requires self-recognition.

John H Lee, Alina P Sergeeva, Göran Ahlsén, Seetha Mannepalli, Fabiana Bahna, Kerry M Goodman, Runzhe Xu, Baljit S Khakh, Joshua A Weiner, Lawrence Shapiro and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

John H Lee *Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA. JohnHLee@mednet.ucla.edu.ORCID 0009-0004-9337-4403
Alina P Sergeeva *Department of Systems Biology, Columbia University, New York, NY, USA.ORCID 0000-0002-8886-4123
Göran AhlsénZuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA.
Seetha MannepalliZuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA.
Fabiana BahnaZuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA.
Kerry M GoodmanZuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA.
Runzhe XuDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, USA.
Baljit S KhakhDepartment of Physiology, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-0939-1218
Joshua A WeinerIowa Neuroscience Institute, The University of Iowa, Iowa City, IA, USA.
Lawrence ShapiroZuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA.ORCID 0000-0001-9943-8819
Barry HonigDepartment of Systems Biology, Columbia University, New York, NY, USA.ORCID 0000-0002-1835-1031
S Lawrence ZipurskyDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, USA. lzipursky@mednet.ucla.edu.ORCID 0000-0001-5630-7181

Funding

Fundamental astrocyte biology in intact neural circuitsR35NS111583 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Baljit Khakh · 2019 to 2026
$7.9M
Training Grant in Neurobehavioral GeneticsT32NS048004 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, OPHOFF, ROEL A · 2004 to 2025
$5.8M
NINDS NIH HHS R35 NS111583NINDS NIH HHS T32 NS048004
6 · The paper itself

Abstract

Self-recognition is a fundamental cellular process across evolution and forms the basis of neuronal self-avoidance

Indexed as

AstrocytesCadherinsMorphogenesisAnimalsCadherin Related ProteinsFemaleHumansMaleMiceProtein BindingProtein IsoformsVisual CortexCadherin Related ProteinsCadherinsGamma-protocadherinsProtein Isoforms

Identifiers

PMID40437095
PMCPMC12862983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.