Evidence map›Paper›PMID 40436996›Full record

ArticleScientific reports2025

Possible break-down of redox homeostasis in Beals-Hecht syndrome.

María Elena Soto, Linaloe Manzano-Pech, Verónica Guarner-Lans, Israel Pérez-Torres

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María Elena SotoResearch Direction Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, 14080, Mexico City, Mexico.
Linaloe Manzano-PechDepartment of Cardiovascular Biomedicine, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, 14080, Mexico City, Mexico.
Verónica Guarner-LansDepartment of Physiology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, 14080, Mexico City, Mexico.
Israel Pérez-TorresDepartment of Cardiovascular Biomedicine, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, 14080, Mexico City, Mexico. israel.perez@cardiologia.org.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beals-Hecht (BH) syndrome is a rare autosomal dominant disorder caused by a mutation of the FBN-2 gene that codifies for fibrillin-2 (FBN-2). Its nosology includes congenital contractural arachnodactyly. The aim of this study was to evaluate the possible breakdown of redox homeostasis in the thoracic aortic aneurysm (TAA) from patients with BH. We determined OS markers such as malondialdehyde (MDA), total antioxidant capacity (TAC), carbonyl groups, glutathione (GSH), thiols the nitrate/nitrite ratio (NO

Indexed as

Aortic Aneurysm, ThoracicHomeostasisAdultAntioxidantsBiomarkersFemaleFibrillin-2HumansMaleMalondialdehydeMiddle AgedOxidation-ReductionOxidative StressAntioxidantsBiomarkersFibrillin-2MalondialdehydeAntioxidant enzymesBeals-Hecht syndromeFBN-2Oxidative stressRedox homeostasis

Identifiers

PMID40436996
PMCPMC12120066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.