ArticleScientific reports2025
Prevalence of menstrual pain and symptoms and their association with age and BMI among Japanese female app users.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Efficacy and safety of desogestrel/ethinylestradiol 150/20 flexible extended regimen (FREEDOM 150/20) in dysmenorrhea: phase 3 study in Japan.F&S reports · 2026Article
- How well do women understand their menstrual cycles? Insights from 383,085 UK based women.Reproductive health · 2026Article
- Are the Previously Reported Risk Factors for Endometriosis Actually Associated With Pain and Infertility Rather Than Endometriosis Itself?Reproductive medicine and biologyReview
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Authors and funding
9 authors.
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Abstract
Menstruation plays a crucial role in women's health, with age and BMI potentially influencing menstrual pain and associated symptoms. This cross-sectional study analyzed data from Japanese female Sofy app users aged 12-51 years, collected between March 4, 2021, and August 17, 2023. After excluding duplicate and incomplete responses, as well as participants using contraceptives or painkillers, a total of 32,556 valid responses were included. Among the participants, 66.83% reported experiencing menstrual pain, with 28.33% describing it as mild, 25.13% as moderate, and 13.31% as severe. The average number of symptoms reported was 3.36, including 2.43 physical and 0.82 emotional symptoms. Abdominal pain and depression were the most common physical and emotional symptoms, respectively. Menstrual pain and the number of symptoms exhibited an inverted U-shaped relationship with age, peaking slightly earlier in life, and a U-shaped relationship with BMI. Participants in the normal BMI range reported the lowest prevalence of menstrual pain, while those who were underweight had the highest prevalence. Generalized Additive Models (GAM) revealed significant interactions between age and BMI for both menstrual pain and the number of symptoms (p < 0.0001). These findings revealed the age-related inverted U-shape and BMI-related U-shape patterns across all outcomes. Menstrual pain prevalence peaked around the mid-twenties, and symptoms decreased as BMI approached the normal range. The findings provide valuable insights into identifying high-risk groups and informing the development of targeted interventions to improve women's health.
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