Evidence map›Paper›PMID 40436820›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling Reaction of Aliphatic Alcohol Derivatives.

Chloe D Wong, Lauren C Bradford, Nadia Hirbawi, Elizabeth R Jarvo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chloe D WongDepartment of Chemistry, University of California, Irvine, California, 92617, USA.
Lauren C BradfordDepartment of Chemistry, University of California, Irvine, California, 92617, USA.
Nadia HirbawiDepartment of Chemistry, University of California, Irvine, California, 92617, USA.
Elizabeth R JarvoDepartment of Chemistry, University of California, Irvine, California, 92617, USA.ORCID https://orcid.org/0000-0002-2818-4038

Funding

Stereoselective Nickel-Catalyzed Coupling and Cascade ReactionsR01GM135603 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI JARVO, ELIZABETH REINHARDT · 2021 to 2024
$1.2M
National Institute of Health NIH R01GM135603National Science Foundation Graduate Research Fellowship ProgramNIGMS NIH HHS R01 GM135603NIGMS NIH HHS R01GM135603
6 · The paper itself

Abstract

Reactions leveraging readily available starting materials are valuable for synthetic utility, especially for late-stage functionalization. Herein, we report a nickel-catalyzed Suzuki-Miyaura cross-coupling (XC) reaction of aliphatic sulfonates with aryl boronic acids. This reaction provides straightforward access to an array of arylated products in good yield. We have established a one-pot protocol allowing for the arylation of alcohols in a single reaction vessel. Additionally, an asymmetric reaction was developed to provide enantioenriched α-aryl and heteroaryl glutarimides in good yield and enantioselectivity.

Indexed as

Aliphatic alcoholAryl glutarimideCross‐coupling reactionsNickel catalysisSuzuki–Miyaura

Identifiers

PMID40436820
PMCPMC12304806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.