Evidence map›Paper›PMID 40436756›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Acute Hepatitis E virus Subtype 3e Infection with Prolonged Jaundice Improved with Inchinkoto.

Kenichi Kishimoto, Hiroshi Tobita, Masatoshi Kataoka, Tomotaka Yazaki, Akihiko Oka, Norihisa Ishimura, Naoki Fujisawa, Shunji Ishihara

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kenichi KishimotoInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Hiroshi TobitaInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Masatoshi KataokaInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Tomotaka YazakiInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Akihiko OkaInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Norihisa IshimuraInternal Medicine II, Faculty of Medicine, Shimane University, Japan.
Naoki FujisawaDivision of Virology, Shimane Prefectural Institute of Public Health and Environmental Science, Japan.
Shunji IshiharaInternal Medicine II, Faculty of Medicine, Shimane University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is a globally prevalent waterborne and zoonotic infection, with approximately 20 million infections occurring annually in developing and industrialized countries. Reported here are the details of a 73-year-old Japanese man who contracted HEV subtype 3e after consuming self-prepared pork liver from a domestically raised pig and presented with severe liver enzyme elevation. Conservative treatment, including hepatoprotective therapy and Inchinkoto, an herbal medicine, was administered for prolonged jaundice, and recovery was achieved. Owing to the long incubation period and nonspecific symptoms, routine HEV testing is crucial for the differential diagnosis of acute liver failure to provide appropriate management.

Indexed as

Drugs, Chinese HerbalHepatitis EHepatitis E virusJaundiceAcute DiseaseAgedAnimalsHumansMaleSwineDrugs, Chinese Herbalacute hepatitishepatitis E virusInchinkotosubtype 3ezoonotic infection

Identifiers

PMID40436756
PMCPMC12740419

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.