Evidence map›Paper›PMID 40436446›Full record

ArticleBMJ open2025

Community burden of acute respiratory infections in Shanghai, a longitudinal cohort study in respiratory pathogens, China, 2024-2027.

Chuchu Ye, Jianxing Yu, Bing Zhao, Yifeng Shen, Xiao Wang, Li Zhang, Xuya Yu, Yan Luo, Ling Xin, Yanxin Xie and 13 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Chuchu Ye *Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Jianxing Yu *School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID http://orcid.org/0000-0002-9696-2460
Bing Zhao *Shanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Yifeng ShenShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Xiao WangShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Li ZhangShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Xuya YuSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan LuoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ling XinSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yanxin XieShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Yilin JiaShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Xinmei ZhouShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Linghui ZhaoShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Yaoyao WangShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China.
Yu LiSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hualei XinSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ting ZhangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lance RodewaldNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Benjamin J CowlingSchool of Public Health, University of Hong Kong, Hong Kong, China.
Weizhong YangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lipeng HaoShanghai Pudong New Area Center for Disease Control and Prevention, Shanghai, China lizhongjiecdc@163.com renliliipb@163.com hlpmail@126.com.
Lili RenNHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China lizhongjiecdc@163.com renliliipb@163.com hlpmail@126.com.
Zhongjie LiSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China lizhongjiecdc@163.com renliliipb@163.com hlpmail@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe are conducting a longitudinal cohort study-the Community Burden of Acute Respiratory Infections in Shanghai-to assess age-stratified incidence, healthcare utilisation and risk factors of influenza virus, respiratory syncytial virus (RSV) and SARS-CoV-2 associated acute respiratory infections (ARIs) in Shanghai, China.

participantsStudy participants were enrolled by family doctors in all 47 community health services centres in Pudong New Area District, Shanghai, China. All permanent residents 6 months and older living in Pudong for at least 6 months were eligible for enrolment; residents who planned to leave Pudong for more than 1 month in the first study year were excluded. During enrolment, study staff conducted baseline assessments of sociodemographics, underlying medical conditions, vaccination history and household and self-rated health status. Study participants are being followed for ARIs for 3 years. Nasopharyngeal and oropharyngeal swab specimens are being obtained from suspected ARI cases. Influenza virus, RSV, SARS-CoV-2 and other respiratory pathogens are tested for by multiplex respiratory pathogen real-time quantitative PCR assays. Illness courses and clinical recoveries of ARI cases are assessed through weekly contact with ARI cases for 28 days post ascertainment. FINDINGS TO DATE: Between 14 October 2024 and 22 November 2024, we enrolled 5387 community residents into the cohort, including 233 children aged from 6 months to 2 years, 278 preschool children aged 3-6 years, 575 school-age children aged 7-18 years, 2150 adults aged 19-64 years and 2151 older adults aged 65+years. All finished baseline assessment and started follow-up. Surveillance of ARI symptoms, collection of specimens and laboratory testing are ongoing. FUTURE PLANS: Findings from this study will be used to provide valuable scientific data to inform ongoing control efforts and future pandemic preparedness for respiratory diseases in China. Planned analyses include analysis of annual pathogen-specific incidence by age group and exploration of healthcare seeking behaviour and factors associated with ARIs and severe ARIs. We will also assess transmission dynamics of common respiratory pathogens in a household transmission subcohort.

Indexed as

COVID-19Influenza, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsAcute DiseaseAdolescentAdultAgedChildChild, PreschoolChinaCost of IllnessFemaleHumansIncidenceInfantChinaEPIDEMIOLOGIC STUDIESEpidemiologyINFECTIOUS DISEASESRespiratory infections

Identifiers

PMID40436446
PMCPMC12121594

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.