Evidence map›Paper›PMID 40436443›Full record

ArticleBMJ open ophthalmology2025

Comparative study on the quality of life and clinical efficacy of orthokeratology lens, defocus spectacle lens and single vision spectacles in myopic children and adolescents in China.

Ruyi Li, Xingru He, Li Lin, Xiaonan Liu, Yibing Zhou, Yang Li, Tingting Zhao, Jiayan Chen, Wei He, Guanghao Qin and 1 more

Abstract readComparative Study
In one paragraph

Article in BMJ open ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruyi LiDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Xingru HeHe University, Shenyang, China.
Li LinDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Xiaonan LiuDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Yibing ZhouDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Yang LiDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Tingting ZhaoDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Jiayan ChenDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Wei HeDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China.
Guanghao QinDepartment of Clinical Research, He Eye Specialist Hospital, Shenyang, China qinguanghao2020@163.com yusile@hsyk.com.cn.ORCID 0000-0003-1596-7970
Sile YuHe University, Shenyang, China qinguanghao2020@163.com yusile@hsyk.com.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate and compare the vision-related quality of life and efficacy between myopic children and adolescents wearing orthokeratology (OK) lens, defocus spectacle (DS) lens and single vision spectacle (SVS).

methodsThis ambispective cohort study involved 93 participants who had worn optical correction lenses (31 OK lens, 31 DS lens and 31 SVS) for 1 year. The Pediatric Refractive Error Profile questionnaire was used to compare the visual-related quality of life after 1 year of lens wear among the three groups. Changes in axial length (AL) and spherical equivalent (SE) at 6 months and 1 year of lens wear across the groups were assessed.

resultsNo significant differences were observed in academics and symptoms among the three groups (p>0.05). The OK lens group scored significantly higher in overall vision, far vision, appearance, satisfaction, activities, peer perception and overall scores than the SVS and DS lens groups (p<0.05). The DS lens group showed significantly lower scores in near vision compared with the OK lens and SVS groups (p<0.05). The OK lens group had a significantly lower handling score than the SVS group (p=0.01), with no significant difference between the OK lens and DS lens groups (p=0.184). In the 12th month, the axial length (AL) changes in the OK lens, DS lens and SVS groups were 0.18±0.08 mm, 0.27±0.08 mm and 0.36±0.09 mm, respectively (p<0.05). The OK lens group had the shortest AL elongation compared with the DS lens and SVS groups (p<0.05). The axial growth of the DS lens group was less than that of the SVS group (p<0.05). At both the 6th and 12th months, both the DS lens group and the SVS group showed an increasing trend in SE, with the SVS group exhibiting a significantly greater increase in SE compared with the DS lens group (p<0.001).

conclusionAlthough both the DS lens and OK lens can effectively control myopia, the OK lens demonstrates superior performance in improving vision-related quality of life and controlling axial elongation. This study is limited by the fact that the lens brands chosen by participants in the three groups were all commonly available brands on the market, and no single brand was selected for comparison.

Indexed as

EyeglassesMyopiaOrthokeratologic ProceduresQuality of LifeRefraction, OcularVisual AcuityAdolescentChildChinaFemaleHumansMalePatient SatisfactionSurveys and QuestionnairesTreatment OutcomeContact lensPublic health

Identifiers

PMID40436443
PMCPMC12121595

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.