Evidence map›Paper›PMID 40435963›Full record

ArticleInternational archives of allergy and immunology2026

Inhalant Allergen Sensitization: Prevalence, Risk Factors, and Geographic Variation in the USA.

Kenny Kwong, Zhen Chen, Lyne Scott, Lee H Hilborne

Abstract read
In one paragraph

Article in International archives of allergy and immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Kenny KwongDepartment of Pediatrics, Los Angeles General Medical Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA, ykwong@dhs.lacounty.gov.
Zhen ChenQuest Diagnostics, Secaucus, New Jersey, USA.
Lyne ScottDepartment of Pediatrics, Los Angeles General Medical Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Lee H HilborneQuest Diagnostics, Secaucus, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: We aimed to assess the prevalence of IgE-mediated sensitization to two perennial (dust mite and animal) and four seasonal allergen sources (tree, grass, weed, and mold/fungi) using data from a national clinical reference laboratory (Quest Diagnostics).

methodsPatients tested in 2019 for ≥1 specific serum IgE toward 4 dust mites, 14 animals, 32 trees, 12 grasses, 21 weeds, or 19 mold/fungi allergens were included. Patients with ≥1 specific IgE ≥0.10 kU/L within a source were considered sensitized for the source. Chi-square tests and multivariate logistic regression were used to compare the estimated prevalence of allergic sensitization related to demographics, geography, and clinical diagnosis.

resultsSensitization for dust mite, animal, tree, grass, weed, and mold/fungi sources was 38.0% (21,161/55,735), 32.1% (21,888/68,035), 34.5% (22,975/66,567), 30.3% (21,664/71,575), 31.2% (22,960/73,605), and 19.7% (13,514/68,574), respectively. Across allergen sources, males had higher prevalence (from lowest to highest: 25.3% mold/fungi to 43.0% dust mite) compared to females (from lowest to highest: 16.1% mold/fungi to 34.6% dust mite); prevalence peaked in 10-19 years (from lowest to highest: 29.7% mold/fungi to 54.2% dust mite) and then decreased with increasing age; large metropolitan areas (from lowest to highest: 39.6% dust mite to 20.7% mold/fungi) had higher prevalence compared to small-to-medium metro (from lowest to highest: 36.6% dust mite to 17.9% mold/fungi) or nonmetro areas (from lowest to highest: 32.4% dust mite to 19.5% mold/fungi); a higher prevalence was observed in patients with asthma, atopic dermatitis, or rhinitis than in those with none of these diagnoses reported. Sensitization to perennial and seasonal allergens showed regional variation.

conclusionsPrevalence of allergic sensitization to perennial and seasonal allergens is associated with patient age and sex, census regions, level of urbanization, and allergic disease states. These factors should be considered when designing and selecting allergen panels for diagnosing and treating symptomatic patients. </p>.

Indexed as

AllergensHypersensitivityAdolescentAdultAgedAnimalsChildChild, PreschoolFemaleGeographyHumansImmunizationImmunoglobulin EMaleMiddle AgedPrevalenceAllergensImmunoglobulin EGeographyInhalant allergenRisk factorsSeasonal allergenSensitizationUSA

Identifiers

PMID40435963
PMCPMC12258866

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