Evidence map›Paper›PMID 40435221›Full record

ArticleFuture science OA2025

The I/D variant of the

Valeriy Pokhylko, Yuliia Cherniavska, Liliia Fishchuk, Zoia Rossokha, Olena Popova, Viktoriia Vershyhora, Olha Dubitska, Liudmyla Zhuk, Svitlana Tsvirenko, Serhii Kovtun and 1 more

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Article in Future science OA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Valeriy PokhylkoDepartment of Pediatrics No. 1 with Neonatology, Poltava State Medical University, Poltava, Ukraine.
Yuliia CherniavskaDepartment of Pediatrics No. 1 with Neonatology, Poltava State Medical University, Poltava, Ukraine.
Liliia FishchukInstitute of Genetic and Regenerative Medicine, SI "National Scientific Center Named after M.D. Strazhesko NAMS of Ukraine", Kyiv, Ukraine.ORCID 0000-0001-9999-7389
Zoia RossokhaShupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Olena PopovaShupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Viktoriia VershyhoraShupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Olha DubitskaShupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Liudmyla ZhukDepartment of Pediatrics No. 1 with Neonatology, Poltava State Medical University, Poltava, Ukraine.
Svitlana TsvirenkoDepartment of Pediatrics No. 1 with Neonatology, Poltava State Medical University, Poltava, Ukraine.
Serhii KovtunPoltava Regional Clinical Infectious Diseases Hospital of Poltava Regional Council, Poltava, Ukraine.
Nataliia GorovenkoInstitute of Genetic and Regenerative Medicine, SI "National Scientific Center Named after M.D. Strazhesko NAMS of Ukraine", Kyiv, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe purpose of our study was to investigate the prevalence of the I/D variant of the PATIENTS AND

methodsThe study group included 117 patients with severe COVID-19 and 100 with mild COVID-19. All patients underwent testing for the I/D variant of the

resultsThe genotype frequencies in the group of patients with severe and mild COVID-19 were as follows: II - 23.1% and 20.0%, ID - 50.4% and 52.0%, DD - 26.6% and 28.0%. These frequencies did not significantly differ from each other, nor did they differ in the population frequencies for the Ukrainian population. The study revealed that the level of diuresis in carriers of the ID genotype was significantly higher than that in patients with the II genotype (p = 0.009). Patients with the DD genotype had prolonged activated partial thromboplastin time compared with those with the ID genotype (p = 0.023).

conclusionsThe I/D variant of the

Indexed as

ACECOVID-19geneI/D variantRAAS

Identifiers

PMID40435221
PMCPMC12123970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.