Evidence map›Paper›PMID 40435041›Full record

ReviewSao Paulo medical journal = Revista paulista de medicina2025

The use of artificial intelligence to identify ophthalmic biomarkers in cardiovascular disease and stroke: a narrative review.

Diogo Gonçalves Dos Santos Martins, Thiago Goncalves Dos Santos Martins, Paulo Schor

Abstract readReview
In one paragraph

Review in Sao Paulo medical journal = Revista paulista de medicina, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Diogo Gonçalves Dos Santos MartinsDepartment of Ophthalmology, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.ORCID 0000-0002-6881-5359
Thiago Goncalves Dos Santos MartinsDepartment of Ophthalmology, Universidade Federal do Rio de Janeiro (UFRJ), Macaé (RJ), Brazil.ORCID 0000-0002-3878-8564
Paulo SchorFree Professorship, Department of Ophthalmology, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.ORCID 0000-0002-3999-4706

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) and stroke are among the leading causes of death worldwide.

objectiveThis article presents a review of the application of artificial intelligence in identifying biomarkers for CVD and stroke. DESIGN AND

settingNarrative review conducted by a research group at the Universidade Federal de São Paulo, São Paulo, Brazil.

methodsA literature search was conducted to identify the main applications of artificial intelligence in ophthalmology, using the keywords "artificial intelligence," "prediction," "biomarker," "cardiovascular disease," "retina," and "stroke," covering the period from January 1, 2018, to July 3, 2023. The Medical Literature Analysis and Retrieval System Online (MEDLINE, via PubMed) and the Latin American and Caribbean Literature in Health Sciences (Literatura Latino-Americana e do Caribe em Ciências da Saúde, LILACS, via the Virtual Health Library) were used to identify relevant articles.

resultsA total of 30 references were retrieved, of which 14 were considered eligible for intensive review and critical analysis.

conclusionsArtificial intelligence has proven effective in identifying non-invasive biomarkers through the analysis of patients' retinal examinations. These findings contribute to a better understanding of the pathophysiology of CVD and stroke.

Indexed as

Artificial IntelligenceBiomarkersCardiovascular DiseasesStrokeHumansBiomarkers

Identifiers

PMID40435041
PMCPMC12105858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.