Evidence map›Paper›PMID 40435007›Full record

Observational studyArquivos brasileiros de cardiologia2025

Is Female Gender Associated with Mortality in Coronary Artery Bypass Grafting?

Maxim Goncharov, Erlon Oliveira de Abreu Silva, Pedro Gabriel Melo de Barros E Silva, Fabiane Letícia de Freitas, Adriana Costa Moreira, Lucas Tramujas, Alexandre Biasi Cavalcanti, Ieda Maria Liguori, Fabio Biscegli Jatene, Ieda Biscegli Jatene and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Arquivos brasileiros de cardiologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nothing about Women without Women is for Women.Arquivos brasileiros de cardiologia · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maxim GoncharovHospital do Coração, São Paulo, SP - Brasil.ORCID 0000-0003-4820-8399
Erlon Oliveira de Abreu SilvaHospital do Coração, São Paulo, SP - Brasil.
Pedro Gabriel Melo de Barros E SilvaHospital do Coração, São Paulo, SP - Brasil.ORCID 0000-0003-1940-4470
Fabiane Letícia de FreitasInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0002-3600-0200
Adriana Costa MoreiraHospital do Coração, São Paulo, SP - Brasil.
Lucas TramujasHospital do Coração, São Paulo, SP - Brasil.
Alexandre Biasi CavalcantiHospital do Coração, São Paulo, SP - Brasil.
Ieda Maria LiguoriHospital do Coração, São Paulo, SP - Brasil.
Fabio Biscegli JateneInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0001-6175-5595
Ieda Biscegli JateneHospital do Coração, São Paulo, SP - Brasil.
Claudia Maria Rodrigues AlvesHospital do Coração, São Paulo, SP - Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen undergoing coronary artery bypass grafting (CABG) tend to have worse in-hospital outcomes, but it is unclear whether these differences are due to gender or to clinical factors.

objectiveTo compare in-hospital outcomes between women and men undergoing CABG.

methodsThis was a single-center, retrospective observational study analyzing data from 9,845 patients who underwent CABG between 1995 and 2022, of whom 1,947 (19.8%) were women. To evaluate female gender as a prognostic factor for in-hospital mortality, we used descriptive statistics, univariate and multivariate logistic regression, and propensity score matching. The significance level was set at 5%.

resultsWomen were older (66.7 vs 62.19 years, p<0.001), had lower body mass index (26.91 vs 27.64, p<0.001), and had a higher prevalence of diabetes mellitus (34.0% vs 31.6%, p=0.045). They also had longer hospital stays (14.84 vs 13.13 days, p<0.001) and higher operative mortality (4.8% vs 2.4%, p<0.001). In logistic regression, female gender was associated with higher mortality (OR=1.51; 95% CI: 1.15-1.99; p=0.003). After matching, there was no significant difference in mortality (OR=1.20; 95% CI: 0.88-1.64; p=0.241), but length of hospital stay remained longer in women.

conclusionWhen clinical factors were matched between men and women, the mortality difference disappeared. This suggests that targeted interventions to reduce disparities may help improve mortality outcomes in women undergoing CABG.

Indexed as

Coronary Artery BypassHospital MortalityAgedAge FactorsFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesRisk FactorsSex FactorsTreatment Outcome

Identifiers

PMID40435007
PMCPMC12129472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.