Evidence map›Paper›PMID 40434607›Full record

ArticlePhysical and engineering sciences in medicine2025

Improvement of lung nodule visibility using one-shot dual-energy subtraction chest radiography with dual-layer flat-panel detector: a phantom study.

Shinya Takarabe, Taku Kuramoto, Yui Kanzaki, Yusuke Shibayama, Yuzo Yamasaki, Yoshiyuki Kitamura, Hideki Yoshikawa, Toyoyuki Kato

Abstract read
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Article in Physical and engineering sciences in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shinya TakarabeDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Taku KuramotoDepartment of Radiological Technology, Faculty of Health Sciences, Kobe Tokiwa University, 2-6-2 Otanicho, Nagata-ku, Kobe, 653-0838, Japan. t-kuramoto@kobe-tokiwa.ac.jp.ORCID http://orcid.org/0000-0002-9209-6171
Yui KanzakiDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yusuke ShibayamaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yuzo YamasakiDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yoshiyuki KitamuraDepartment of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Hideki YoshikawaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Toyoyuki KatoDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Funding

Fukuoka Public Health Promotion Organization Cancer Research Fund GAKF800586
6 · The paper itself

Abstract

Chest x-ray imaging is widely used for the diagnosis of chest diseases but has low sensitivity for detecting pulmonary nodules due to anatomical overlaps. Dual-energy subtraction (DES) imaging can improve nodule visibility by reducing bone obscuration. This study aims to evaluate the image quality of a new one-shot DES (OSDES) system with a dual-layer flat-panel detector compared with the widely used two-shot DES (TSDES) system. Chest phantom images of various simulated nodules (8,10, and 12 mm) were acquired using both DES systems at several exposure doses, lung regions, and two types of body sizes (standard and large). Independent observers evaluated the visibility of the nodules under each condition using visual grading analysis scores (VGASs). The VGASs of OSDES images were significantly higher than those of TSDES images across all nodule sizes, lung regions, exposure doses, and body sizes, except for the standard chest phantom with a 10-mm nodule and without ribs. In particular, the VGAS of an 8-mm nodule in the region with one overlapping rib of the standard sized phantom was 2.46 with OSDES and 1.03 with TSDES, with the visibility of the nodule being significantly improved with the OSDES system. Thus, the OSDES system, using a dual-layer flat-panel detector and one exposure, offers superior visibility of pulmonary nodules with reduced dose compared with the TSDES system, suggesting its potential for improved clinical diagnosis without motion artifacts.

Indexed as

Chest X-ray imagingDual-energy Subtraction imagingImage qualityVisual grading analysis

Identifiers

PMID40434607

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.