Evidence map›Paper›PMID 40434601›Full record

ArticleAging clinical and experimental research2025

Predicting working memory efficiency across adulthood: the role of enhancement and suppression attentional mechanisms, moderated by age and other factors.

Elissa López-González, Ulises Caballero-Sánchez, Ixchel Gómez-González, Mónica Méndez-Díaz, Oscar E Prospéro-García, Alejandra E Ruiz-Contreras

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elissa López-GonzálezLaboratorio de Neurogenómica Cognitiva, Unidad de Investigación de Psicobiología y Neurociencias, Coordinación de Psicobiología y Neurociencias, Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Ulises Caballero-SánchezLaboratorio de Neurogenómica Cognitiva, Unidad de Investigación de Psicobiología y Neurociencias, Coordinación de Psicobiología y Neurociencias, Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Ixchel Gómez-GonzálezLaboratorio de Neurogenómica Cognitiva, Unidad de Investigación de Psicobiología y Neurociencias, Coordinación de Psicobiología y Neurociencias, Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Mónica Méndez-DíazLaboratorio de Cannabinoides, Departamento de Fisiología, Facultad de Medicina, UNAM, Mexico City, Mexico.
Oscar E Prospéro-GarcíaLaboratorio de Cannabinoides, Departamento de Fisiología, Facultad de Medicina, UNAM, Mexico City, Mexico.
Alejandra E Ruiz-ContrerasLaboratorio de Neurogenómica Cognitiva, Unidad de Investigación de Psicobiología y Neurociencias, Coordinación de Psicobiología y Neurociencias, Facultad de Psicología, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico. aleruiz@unam.mx.

Funding

Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT) IN202822Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT) IN217221
6 · The paper itself

Abstract

The global population of individuals aged 60 years and older now exceeds one billion and continues to grow, underscoring the necessity of addressing cognitive challenges associated with aging. The present study aimed to evaluate the enhancement and suppression of attentional mechanisms, as well as working memory efficiency (WME), across the adult lifespan. Additionally, it examined factors that may moderate these relationships. A total of 194 participants, aged between 20 and 80 years, completed questionnaires and participated in an experimental task designed to assess attentional mechanisms and WME. The results indicated that both enhancement and suppression mechanisms remained stable throughout adulthood; however, WME showed a decline with increasing age. Notwithstanding, several moderating variables influenced these outcomes. Cognitive reserve and current cognitive functioning were found to be positive predictors of WME, whereas depression and anxiety exerted negative effects. Furthermore, a low level of cognitive reserve uniquely predicted diminished suppression of irrelevant information with advancing age. WME was consistently lower across all ages among participants with high levels of depression, in contrast to those with low or moderate levels, in whom WME followed the expected age-related trajectory. Additionally, elevated anxiety levels and an average sleep duration of five hours were associated with reduced WME, particularly in relation to the enhancement mechanism. Conversely, low levels of depression were linked to improved WME via the enhancement mechanism. These findings underscore the importance of moderating factors that may mitigate cognitive decline or support cognitive functioning throughout the aging process.

Indexed as

AgingAttentionMemory, Short-TermAdultAgedAged, 80 and overAge FactorsAnxietyCognitive ReserveDepressionFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAttentionCognitionCognitive reserveMental healthSleepWorking memory

Identifiers

PMID40434601
PMCPMC12119677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.