Evidence map›Paper›PMID 40434580›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Protection of the ligamentum flavum reduces epidural fibrosis formation in endoscopic lumbar discectomy.

Abdullah Merter, Orhun Eray Bozkurt, Ilyas Dolas, Elif Peker, Sena Unal, Duran Sahin, Ebru Dumlupinar

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Ligamentum flavum preservation via unilateral biportal endoscopy in lumbar discectomy: a "Door-Opening" technique and its clinical outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Letter to the Editor concerning "Protection of the ligamentum flavum reduces epidural fibrosis formation in endoscopic lumbar discectomy" by Merter et al. (European Spine Journal).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdullah MerterAnkara University Faculty of Medicine, Ankara, Turkey.
Orhun Eray BozkurtKulu State Hospital, Konya, Turkey. borhuneray1803@gmail.com.
Ilyas DolasIstanbul University Istanbul Faculty of Medicine, istanbul, Turkey.
Elif PekerAnkara University Faculty of Medicine, Ankara, Turkey.
Sena UnalAnkara University Faculty of Medicine, Ankara, Turkey.
Duran SahinIstanbul University Istanbul Faculty of Medicine, istanbul, Turkey.
Ebru DumlupinarAnkara University, Institute of Health Sciences, Biostatistics, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLumbar disc herniation is a prevalent condition that leads to lower back pain, weakness, and claudication. While microdiscectomy has long been the gold standard for surgical treatment, advances in technology have introduced endoscopic techniques, such as Unilateral Biportal Endoscopic spine surgery. Despite these advances, epidural fibrosis remains a common complication that, potentially hinders recovery and complicating revision surgeries. This study aimed to compare the extent of epidural fibrosis between microdiscectomy and UBE surgery with preserved flavum and flavectomy.

methodsThis retrospective study included 47 patients diagnosed with lumbar disc herniation who underwent surgery between August 2020 and July 2022 at two tertiary university hospitals. The patients underwent endoscopic surgery with flavum preservation (n = 16), flavum excision (n = 16), lumbar microdiscectomy with flavectomy (n = 15). Preoperative and postoperative imaging, including X-rays, computed tomography, and magnetic resonance imaging were performed. Functional scores (Visual Analog Scale, Japanese Orthopedic Association score, and Oswestry Disability Index were assessed. Postoperative magnetic resonance imaging was conducted at three months to evaluate epidural fibrosis.

resultsThe rate of epidural fibrosis was significantly lower in the flavum sparing UBE (0.18 ± 0.17) compared to the flavum non-sparring UBE (0.38 ± 0.19) and the flavum non-sparring microdiscectomy (0.47 ± 0.18) (p < 0.001). Functional scores significantly improved postoperatively in all groups, with significant differences noted in JOA, Oswestry, and VAS scores (p < 0.01). Early functional score differences between the groups were found to be significant in favor of UBE, particularly in the flavum-sparing group.

conclusionThe preservation of flavum during UBE surgery leads to significantly less epidural fibrosis compared to both flavum non-sparring UBE and microdiscectomy. Functional improvements were similar across groups, but flavum sparring UBE surgery demonstrated better early postoperative outcomes. The results suggest that preserving flavum during endoscopic spine surgery may reduce epidural fibrosis formation and promote better recovery, supporting the benefits of minimally invasive techniques in lumbar disc herniation surgery.

Indexed as

DiskectomyEndoscopyEpidural SpaceIntervertebral Disc DisplacementLigamentum FlavumLumbar VertebraePostoperative ComplicationsAdultAgedFemaleFibrosisHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesEpidural fibrosisFlavum sparringLumbar disc herniationMicrodiscectomyUnilateral biportal endoscopy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.