ArticleEmergency radiology2025
Wide-Detector CT-Based optimized triple Rule-Out CT angiography for emergency chest pain: reducing contrast and radiation without compromising diagnostic quality.
Article in Emergency radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Single-Bolus Sequential Triple-Rule-Out CT Angiography: Image Quality and Radiation Dose on Wide-Area Detector and Dual-Source CT.Journal of clinical medicine · 2026Article
- Sequential Helical-Axial-Helical Triple-Rule-Out CT Angiography: Technical Feasibility and Territory-Specific Image Quality in the Emergency Department.Journal of clinical medicine · 2026Article
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Authors and funding
3 authors.
Funding
Abstract
backgroundThe triple rule-out computed tomography angiography (TRO-CTA) has recently emerged as a technique that noninvasively evaluates the coronary arteries (CAs), the pulmonary arteries (PAs) and the thoracic aorta (TA).
objectiveTo evaluate the feasibility of an optimized scanning protocol to reduce the volume of iodine contrast media (ICM), injection rate, and radiation dose in patients undergoing TRO-CTA.
methodsPatients undergoing TRO-CTA were assigned to either group A or group B using a 16 cm wide-detector CT. Patients in group A were imaged with a traditional triple scanning protocol with a sequence of the PA, CAs, and TA. Patients in group B were imaged using the modified protocol with scanning sequence of PA, TA, and CAs, ICM of 55 ml, and injection rate of 4.5 mL/s. The image quality and effective radiation dose (ED) were compared.
resultsThere were no significant differences in basic information between groups A and B. Other than the left PA, RA, and RV, there were no significant differences in the CT attenuation values of relevant vascular structures between groups A and B. There were no significant differences in CNR values between the two groups except the LAD-D and LCX. The image quality scores were comparable between groups A and B except the CAs. However, there were significant differences between the two groups in ICM (p < 0.05), scanning time (p < 0.001) and ED (p = 0. 023).
conclusionsThe optimized TRO-CTA scanning protocol can achieve less ICM and lower ED while maintaining image quality.
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