Evidence map›Paper›PMID 40434508›Full record

ReviewMolecular biology reports2025

Migrasome: a novel insight into unraveling physiological and pathological function.

Yu Ye, Jun Zhang, Yue Liu, Xiaochun Sun

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu Ye *School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Jun Zhang *Department of Laboratory, The Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225001, China.
Yue LiuSchool of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Xiaochun SunSchool of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China. xiaochun@ujs.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The migrasome, a recently discovered organelle formed during cell migration, is a membrane-bound vesicular structure containing numerous smaller intracavitary vesicles and cellular contents. It is generated at the tips and intersections of retraction fibers (RFs). Upon the rupture of RFs, migrasomes can either be engulfed by surrounding cells or undergo lysis to release their contents into the extracellular microenvironment. The process through which cells release their contents via migrasomes is termed migracytosis. Migrasomes play crucial roles in intercellular signaling, cellular homeostasis maintenance, and intercellular material transport. This article provides a comprehensive review of the discovery, biogenesis, isolation and characterization, biological functions of migrasomes, as well as their roles in the occurrence, progression, diagnosis, and treatment of clinical diseases. Furthermore, this paper proposes novel hypotheses and future directions regarding the current research challenges of migrasomes and their potential clinical applications, which may facilitate future clinical diagnosis and treatment involving migrasomes.

Indexed as

Cell MovementExtracellular VesiclesOrganellesAnimalsHumansSignal TransductionCell migrationDisease progressionMigrasomesOrganelle

Identifiers

PMID40434508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.