Evidence map›Paper›PMID 40434228›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Wideband Tuning and Deep-Tissue Spectral Detection of Indium Phosphide Nano-Laser Particles.

Sangyeon Cho, Wonjoon Moon, Nicola Martino, Seok Hyun Yun

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Sangyeon ChoHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Cambridge, Massachusetts, 02139, USA.ORCID https://orcid.org/0000-0002-2997-4760
Wonjoon MoonHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Cambridge, Massachusetts, 02139, USA.ORCID https://orcid.org/0000-0003-2875-3760
Nicola MartinoHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Cambridge, Massachusetts, 02139, USA.ORCID https://orcid.org/0000-0002-4639-2930
Seok Hyun YunHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Cambridge, Massachusetts, 02139, USA.ORCID https://orcid.org/0000-0002-8903-5909

Funding

Laser particles for multi-dimensional single-cell analysisR01EB033155 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI YUN, SEOK-HYUN ANDY · 2021 to 2025
$3.5M
Multi-color laser particles for high-throughput pooled analysisR01EB034687 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Seok-Hyun Andy Yun · 2023 to 2026
$2.0M
National Science Foundation 1541959NIBIB NIH HHS R01 EB033155NIBIB NIH HHS R01 EB034687NIH HHS R01-EB033155NIH HHS R01-EB034687
6 · The paper itself

Abstract

Laser particles (LPs) emitting narrowband spectra across wide spectral ranges are highly promising for high-multiplex optical barcoding of biological cells. Here, LPs based on indium phosphide (InP) nanodisks are presented, operating in the near-infrared wavelength range of 740-970 nm. Utilizing low-order whispering gallery resonance modes in size-tuned nanodisks, an ultrawide color palette with 25% spectral utilization and nanometer-scale linewidth is achieved. A simple theoretical model accurately predicts spectral ranges based on particle size. The minimum laser size is 430 nm in air and 560 nm within cells, operating at mode orders of 4 or 5. The high brightness and narrow linewidths of polymer-silica-protected InP LPs, combined with a silicon-detector spectrometer, enable spectral detection of laser peaks with high signal-to-background ratios in highly-scattering media, including 1-cm-thick chicken breast tissue and blood vessels in live mice.

Indexed as

IndiumLasersNanoparticlesPhosphinesAnimalsChickensMiceParticle SizeIndiumindium phosphidePhosphinesdeep tissueIII/V semiconductorin vivo imagingnanolasersingle cell study

Identifiers

PMID40434228
PMCPMC12354337

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.