Evidence map›Paper›PMID 40434035›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment.

Wei-Chung Pan, Cheng-Hung Luo, Wen-Ling Lin, Liu-Chun Wang, Divinah Manoharan, Po-Ya Chang, Hwo-Shuenn Sheu, Chen-Hao Yeh, Chia-Jui Yen, Chen-Sheng Yeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei-Chung PanDepartment of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan.
Cheng-Hung LuoDepartment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan.ORCID https://orcid.org/0000-0002-3589-971X
Wen-Ling LinDepartment of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan.
Liu-Chun WangDepartment of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan.ORCID https://orcid.org/0000-0002-9170-0509
Divinah ManoharanDepartment of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan.ORCID https://orcid.org/0000-0001-8208-5594
Po-Ya ChangNational Synchrotron Radiation Research Center, Hsinchu, 30076, Taiwan.
Hwo-Shuenn SheuNational Synchrotron Radiation Research Center, Hsinchu, 30076, Taiwan.ORCID https://orcid.org/0000-0003-1334-5895
Chen-Hao YehDepartment of Materials Science and Engineering, Feng Chia University, Taichung, 40724, Taiwan.ORCID https://orcid.org/0000-0001-5665-6496
Chia-Jui YenDepartment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan.
Chen-Sheng YehDepartment of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan.ORCID https://orcid.org/0000-0001-5102-3884

Funding

National Science and Technology Council 112-2113-M-035 -001 -MY3National Science and Technology Council 113-2113-M-006-015
6 · The paper itself

Abstract

This study introduces a novel approach to cancer treatment using covalent organic frameworks (COFs) with dual atomic metal sites, employing a galvanic reaction to integrate both gold (Au) and iridium (Ir) onto COF (COF/Au

Indexed as

GlucoseNeoplasmsReactive Oxygen SpeciesAnimalsCatalysisCell Line, TumorGoldHumansHydrogen PeroxideIridiumMetal-Organic FrameworksMiceOxidation-ReductionGlucoseGoldHydrogen PeroxideIridiumMetal-Organic FrameworksReactive Oxygen Speciescatalasecovalent organic frameworksdual‐atom catalystgalvanic replacementglucose oxidasehaloperoxidase

Identifiers

PMID40434035
PMCPMC12362782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.