Evidence map›Paper›PMID 40433910›Full record

ReviewJournal of materials chemistry. B2025

Chemical imaging for biological systems: techniques, AI-driven processing, and applications.

Ying Cui, Zhihan Zhang, Yuan Shi, Yongjie Hu

Abstract readReview
In one paragraph

Review in Journal of materials chemistry. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ying CuiHenry Samueli School of Engineering and Applied Science, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Zhihan ZhangHenry Samueli School of Engineering and Applied Science, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Yuan ShiDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID http://orcid.org/0000-0002-9993-0448
Yongjie HuHenry Samueli School of Engineering and Applied Science, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID http://orcid.org/0000-0001-7225-1130

Funding

Nanoscale Temperature Mapping and Thermal Regulation of Intracellular DynamicsR35GM147391 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yongjie Hu · 2022 to 2026
$2.2M
Mechanism for anti-interferon functions of influenza virusR01AI143287 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHI, YUAN · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI143287NIGMS NIH HHS R35 GM147391
6 · The paper itself

Abstract

Visualizing the chemical compositions of biological samples is pivotal to advancing biological sciences, with the past two decades witnessing the emergence of innovative chemical imaging platforms such as single-molecule imaging, coherent Raman scattering microscopy, transient absorption microscopy, photothermal microscopy, ambient ionization mass spectrometry, electrochemical microscopy, and advanced chemical probes. These technologies have enabled significant breakthroughs in diagnosing pathological transitions, designing targeted therapies, and understanding drug resistance mechanisms. Recent advancements in resolution, contrast, sensitivity, and speed have transformed the field, with techniques like fluorescence, infrared absorption, and Raman scattering being widely applied across diverse biological domains. This review provides a comprehensive overview of the evolution and current state of chemical imaging technologies, coupled with systematic analyses of data processing workflows, including pre-processing, machine learning-assisted pattern extraction, and neural network-based predictions. Artificial intelligence (AI) and machine learning-assisted imaging are transforming chemical imaging through key advancements such as improved resolution and sensitivity

Indexed as

Artificial IntelligenceAnimalsHumansMachine LearningOptical Imaging

Identifiers

PMID40433910
PMCPMC12208185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.