Evidence map›Paper›PMID 40433818›Full record

ArticleBiotechnology and bioengineering2025

N- to C-Glycoside Rearrangement of Uridine 5'-Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5'-Phosphate.

Martin Pfeiffer, Franziska Guld, Bernd Nidetzky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology and bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Martin PfeifferInstitute of Biotechnology and Biochemical Engineering, Graz University of Technology, Graz, Austria.ORCID https://orcid.org/0000-0002-0907-2794
Franziska GuldInstitute of Biotechnology and Biochemical Engineering, Graz University of Technology, Graz, Austria.
Bernd NidetzkyInstitute of Biotechnology and Biochemical Engineering, Graz University of Technology, Graz, Austria.ORCID https://orcid.org/0000-0002-5030-2643

Funding

The COMET center acib: Next Generation Bioproduction is funded by BMK, BMDW, SFG, Standortagentur Tirol, Government of Lower Austria und Vienna Business Agency in the framework of COMET - Competence Centers for Excellent Technologies. The COMET-Funding Program is managed by the Austrian Research Promotion Agency FFG.
6 · The paper itself

Abstract

Pseudouridine (Ψ) is an essential building block of synthetic RNA for medical applications, so methods for its efficient production receive increased interest. Reverse reaction of the Ψ-5'-phosphate (ΨMP) C-glycosidase, that is, d-ribose 5-phosphate (Rib5P) + uracil (Ura) → ΨMP + H

Indexed as

GlycosidesPseudouridineUridine MonophosphateEscherichia coliC-glycosideGlycosidesPseudouridineUridine Monophosphatecascade biocatalysispseudouridinepseudouridine 5’‐phosphatepurine/pyrimidine nucleotide 5’‐phosphate nucleosidase (EC 3.2.2.10)ribose 5’‐phosphateuridine 5’‐phosphate

Identifiers

PMID40433818
PMCPMC12322656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.