Evidence map›Paper›PMID 40433703›Full record

ArticleCirculation research2025

Cardiac Ketone Body Oxidation Enhances Exercise Performance.

Kara R Gouwens, Ernesto Pena Calderin, Jada Okhiria, Daniel C Nguyen, Emily B Schulman-Geltzer, Yania Martinez-Ondaro, Maleesha De Silva, Helen E Collins, Yibing Nong, Sophia M Sears and 2 more

Erratum issuedAbstract readLetter
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kara R GouwensCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0001-5516-7586
Ernesto Pena CalderinCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0002-4403-9543
Jada OkhiriaCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0009-0008-8455-8314
Daniel C NguyenCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0002-9268-0300
Emily B Schulman-GeltzerCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0009-0004-7893-0838
Yania Martinez-OndaroCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.
Maleesha De SilvaCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0009-0005-9892-2592
Helen E CollinsCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0002-9302-6044
Yibing NongCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0001-7934-7821
Sophia M SearsCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0003-2396-5385
Matthew A NystoriakDepartment of Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, NY (M.A.N.).ORCID 0000-0001-8872-158X
Bradford G HillCenter for Cardiometabolic Science, Envirome Institute, School of Medicine (K.R.G., E.P.C., J.O., D.C.N., E.B.S.-G., Y.M.-O., M.D.S., H.E.C., Y.N., S.M.S., B.G.H.), University of Louisville, KY.ORCID 0000-0001-5332-8286

Funding

TBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI O'TOOLE, TIMOTHY E · 2018 to 2022
$6.3M
Regulation of Coronary Blood FlowR01HL142710 · NHLBI · UNIVERSITY OF LOUISVILLE · PI NYSTORIAK, MATTHEW A · 2018 to 2022
$3.1M
Biosynthetic Pathways in Cardiac RemodelingR01HL147844 · NHLBI · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY, JONES, STEVEN P · 2019 to 2022
$3.0M
Mechanisms Contributing to Pregnancy-induced Cardiac RemodelingR01HL163003 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Helen E Collins · 2023 to 2026
$2.1M
Role of the PEP cycle in cardiac fibrosisR01HL168198 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Bradford Guy Hill · 2024 to 2026
$1.7M
Metabolic regulation of myocardial perfusion in the aging heartR01AG084688 · NIA · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY, NYSTORIAK, MATTHEW A · 2024 to 2024
$508k
Imaging and Physiology Core: High Frequency, High Resolution Ultrasound Imaging SystemS10OD025178 · OD · UNIVERSITY OF LOUISVILLE · PI JONES, STEVEN P · 2019 to 2019
$364k
High fat diet-induced adrenergic dysfunction and resolution of adipose inflammationF31DK131920 · NIDDK · UNIVERSITY OF LOUISVILLE · PI PENA CALDERIN, ERNESTO HECTOR · 2022 to 2024
$84k
NHLBI NIH HHS R01 HL142710NHLBI NIH HHS R01 HL147844NHLBI NIH HHS R01 HL163003NHLBI NIH HHS R01 HL168198NIA NIH HHS R01 AG084688NIDDK NIH HHS F31 DK131920NIGMS NIH HHS P30 GM127607NIH HHS S10 OD025178
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingdietary supplementsexercise toleranceheart failuremetabolismmyocytes, cardiacvasodilation

Identifiers

PMID40433703
PMCPMC12226228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.