ArticleJournal of oral microbiology2025
Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria.
Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
Background: Antibiotics are used in periodontal therapy in selected cases, but therapy is rarely guided by antimicrobial susceptibility testing (AST). Direct AST of the oral microbiota using a combination disk with different antibiotics could provide a new way of AST to guide treatment planning. Methods: We performed AST of 46 strains of Results: The IZD of the AMX-MET correlated with the AMX for Conclusion: The IZD of AMX-MET was comparable to that of AMX and MET for important periodontal pathogens, which opens for studies on direct AST of oral samples with a mixed microbiota. Key message: The amoxicillin-metronidazole disk for antimicrobial susceptibility testing results in comparable inhibition zone diameters to that of AMX and MET for important periodontal pathogens.
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