ArticleFrontiers in neurology2025
Grey-to-white matter ratio on computed tomography for predicting neurological outcome in patients with heat stroke: a retrospective cohort study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Grey-to-white matter ratio (GWR) is an early and sensitive indicator of cerebral oedema in patients with hypoxic-ischaemic brain injury, we aimed to evaluate the prognostic value of GWR for predicting neurological outcome in heat stroke patients. Methods: This multicentre retrospective analysis included 86 patients with heat stroke patients who underwent cranial computed tomography (CT). Patients were stratified by Cerebral Performance Category (CPC) scores at discharge: good outcome (CPC 1-2, Results: All GWRs were significantly lower in the poor outcome group than in the good outcome group. ROC analysis showed the following areas under the curve: PU/CC, 0.836; CN/PLIC, 0.815; CN/CC, 0.858; PU/PLIC, 0.814; GWR Discussion: A low GWR was strongly associated with poor outcome in the heat stroke patients. The GWR may be useful as an objective early predictor of poor neurological outcome in the heat stroke patients. Incorporating the GWR with qSOFA significantly enhanced the prediction performance.
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