Evidence map›Paper›PMID 40433495›Full record

SynthesisFrontiers in neuroscience2025

Transcranial ultrasound stimulation in neuromodulation: a bibliometric analysis from 2004 to 2024.

Jingxuan Wang, Yuling Wang, Shuyan Qie

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jingxuan WangBeijing Rehabilitation Medicine, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Yuling WangDepartment of Orthopedics II, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Shuyan QieDepartment of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcranial ultrasound stimulation (TUS) is a non-invasive neuromodulation technique with promising clinical potential. Its therapeutic efficacy and safety are significantly influenced by stimulation parameters. However, the global research hotspots and future research trends of TUS application in the field of rehabilitation are unclear. This study analyzes the status of TUS research. Understand the annual publication trends, international and institutional cooperation pattern and influential authors and journals and keyword hotspot. Methods: A comprehensive literature search was conducted on the Web of Science core database using TUS-related subject headings until 27 December 2024. Two researchers independently screened articles based on pre-determined inclusion and exclusion criteria. Software packages such as CiteSpace and VOSviewer were used to visualize the results. Results: A total of 577 literatures were included. The results show that the annual publication volume shows an increasing trend, reaching a peak in 2024. The United States, China and Germany dominated the number of publications, with the largest number of institutions being Harvard University, the University of Toronto and Brigham and Women's Hospital. Brain stimulation is the journal with the most articles and citations. Research hotspots include transcranial magnetic stimulation, noninvasive brain stimulation, Parkinson's disease, and Alzheimer's disease. Conclusion: A bibliometric analysis of the literature shows that research interest in transcranial ultrasound stimulation is growing rapidly, with annual publications growing exponentially since 2013 and receiving increasing attention from researchers. The findings suggest that TUS is currently used primarily in neurological diseases, particularly in the study of Parkinson's disease and Alzheimer's disease. At the same time, it is found that an emerging international cooperation model with the partnership between the United States, China and Germany as the core has gradually taken shape. Although preclinical studies have shown promising neuromodulator effects, the current study suggests that TUS needs to undergo further multicenter clinical validation. These findings provide evidence to guide future research priorities for non-invasive neuromodulation.

Indexed as

bibliometric analysisneuromodulationnon-invasive brain stimulationphysiotherapytranscranial ultrasound stimulation

Identifiers

PMID40433495
PMCPMC12106416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.