Evidence map›Paper›PMID 40433463›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025

Association Between Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Insulin Resistance in Mongolian Adults.

Galsanjigmed Narkhajid, Byambasukh Oyuntugs, Altangerel Yagaantsetseg, Enkhtuvshin Bolormaa, Erdembileg Anuurad, Byambaa Enkhmaa, Lars Berglund, Tumenbayar Bayasgalan

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Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Galsanjigmed Narkhajid *Department of Endocrinology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, 13270, Mongolia.ORCID 0009-0003-1547-6124
Byambasukh OyuntugsDepartment of Endocrinology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, 13270, Mongolia.
Altangerel YagaantsetsegPostgraduate Training Institute, Mongolian National University of Medical Sciences, Ulaanbaatar, 14210, Mongolia.
Enkhtuvshin BolormaaIntermed Hospital, Ulaanbaatar, Mongolia.
Erdembileg AnuuradOffice of Research, School of Medicine, University of California - Davis, Sacramento, CA, 95817, USA.
Byambaa EnkhmaaDepartment of Internal Medicine, School of Medicine, University of California - Davis, Davis, CA, USA.
Lars BerglundDepartment of Internal Medicine, School of Medicine, University of California - Davis, Davis, CA, USA.ORCID 0000-0001-6705-1791
Tumenbayar Bayasgalan *Postgraduate Training Institute, Mongolian National University of Medical Sciences, Ulaanbaatar, 14210, Mongolia.ORCID 0000-0001-8459-4253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: While the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) is widely used to identify insulin resistance, its clinical utility can be cumbersome. An alternative, the triglyceride-to-high-density lipoprotein cholesterol (TG/HDL) ratio, offers simplicity but may exhibit variability across different populations. This study aimed to investigate its association with HOMA-IR adjusting for waist circumference among Mongolian adults. Materials and Methods: This cross-sectional study, conducted at the Mongolian National University of Medical Sciences Hospital, included 365 participants over 35 who participated in health check-up examinations (mean age 46.8 ± 8.8 years, 37.0% male). Waist circumference was categorized into tertiles. Associations between the TG/HDL ratio and HOMA-IR were meticulously assessed within the waist circumference tertiles (0-33.3%, 33.4-66.6%, and 66.7-100%), ensuring a comprehensive understanding of the data. Results: A significant positive correlation (r = 0.391, p = 0.019) was observed between the TG/HDL ratio and HOMA-IR levels in all participants. Analyses by waist circumference tertiles revealed a progressively stronger correlation (ranging from r = 0.241 to 0.469) with increasing waist circumference (p <0.05). The diagnostic accuracy of the TG/HDL ratio in identifying insulin resistance was assessed using HOMA-IR thresholds of 2.0 and 2.5, yielding AUC values of 0.693 and 0.746, respectively. When considering waist circumference thresholds (> 90 cm for men and >80 cm for women), TG/HDL ratio thresholds of 1.2 (sensitivity 56%, specificity 90%) in men and 0.69 (sensitivity 46%, specificity 80%) in women were identified. Conclusion: The study indicates that the TG/HDL ratio, adjusted for waist circumference, could be a useful marker for insulin resistance in Mongolian adults, supporting its potential in clinical practice.

Indexed as

HOMA-IRinsulin resistanceTG/HDL ratiowaist circumstance

Identifiers

PMID40433463
PMCPMC12108954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.