ArticleJAC-antimicrobial resistance2025
Magnitude, predictors, and trends of multidrug-resistant tuberculosis among tuberculosis patients at Debre Markos, Northwest, Ethiopia: a five-year retrospective study.
Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The emergence of multidrug-resistant tuberculosis (MDR-TB) is a threat to the people of resource-limited countries, such as Ethiopia. This study aimed to assess the magnitude, predictors and trends of multidrug-resistant tuberculosis among patients with pulmonary tuberculosis (TB) at Debre Markos Comprehensive and Specialized Hospital (DMCSH), Northwest Ethiopia. Materials and Methods: A retrospective cross-sectional study was conducted among patients with TB treated at the directly observed treatment short course (DOTS) clinic at DMCSH from 1 June 2016 to 1 June 2020. Data from 1509 patients with TB registered in the clinic were retrieved from medical records. Statistical analysis was performed using SPSS v.24. The frequency of variables is presented via tables and figures. Logistic regression was fitted to predictors of MDR-TB, and a Results: Overall, data from 1509 patients with pulmonary TB were retrieved during the study. The overall prevalence of MDR-TB was 4.1%. Variables such as sex, human immunodeficiency virus (HIV) status, lesion on chest X-ray, and a history of anti-TB treatment were significantly associated with MDR-TB. The trend of MDR-TB decreased by 40% in 2017, 29% in 2018, and 10% in 2019, but increased by 21% in 2020. Conclusions and recommendations: The prevalence of MDR-TB among patients with pulmonary TB was comparable to the national rate. Key risk factors for MDR-TB included male sex, prior TB treatment, HIV infection, and chest X-ray abnormalities. The increasing trend in 2020 highlights the need for strengthened TB treatment adherence counselling and further prospective studies to explore additional predictors of MDR-TB.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.