ArticleJournal of the Pediatric Orthopaedic Society of North America2024
Understanding the importance of peak bone mass.
Article in Journal of the Pediatric Orthopaedic Society of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Associations between BMI trajectories and young adult bone: a 10-yr follow-up from the Norwegian Fit Futures cohort.JBMR plus · 2026Article
- Micronutrients and omega-3 PUFAs to promote healthy ageing: informing a physiology-based complementation strategy.GeroScience · 2026Review
- Osteoporosis genetic risk prediction using bone mineral density polygenic scores in Japanese: TMM CommCohort study.Journal of human genetics · 2026Article
- Review
- Mechanistic Insights into Milk Minerals Driving Bone Development and Mineralization in Growing Rats.Nutrients · 2026Article
- Primary functional hypothalamic amenorrhoea in the context of feeding and eating disorders or excessive exercise: Insights from non-athletic and elite athletic populations.Journal of neuroendocrinology · 2026Review
- Low-energy hip fracture in a socially withdrawn and physically inactive teenager highlighting the age-independent role of mechanical loading and nutrition: a case report.Journal of medical case reports · 2026Article
- Incidence, Anatomic Distribution, and Return to Training After Stress Fractures in Okinawan Athletes.Orthopaedic journal of sports medicine · 2026Article
- Long-term association between phthalate exposure in pregnancy and midlife bone mineral density among women in Mexico City.Environmental health : a global access science source · 2026Article
- Effect of a Synbiotic Combination of 2'-Fucosyllactose andNutrients · 2026Article
- Calcium Intake and Food Sources Among Children, Adolescents and Women in Madagascar: Results from a Nationally Representative Survey.Nutrients · 2026Article
- Bone and body composition by DXA in girls with precocious puberty, premature thelarche, and prepubertal controls.Journal of the Endocrine Society · 2026Article
- Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass.Journal of the Endocrine Society · 2026Article
- Assessment of peak bone mineral density and its associated factors in Vietnamese adults: A cross-sectional study.PloS one · 2026Article
- Prevalence, patterns and motives for hormonal contraceptive use among German servicewomen: results from a nationwide survey.Frontiers in endocrinology · 2026Article
- Predictors of osteoporosis self-efficacy among young and middle-aged female nurses based on self-efficacy theory and the health belief model: evidence from a tertiary hospital in Eastern China.Frontiers in public health · 2026Article
- Novel insights into the biology of childhood arthritis- lessons learned from the synovium.Arthritis research & therapy · 2025Review
- Impact of Therapeutic Alcohol Administration on Perioperative Quality of Life (QoL) and Fracture Healing in Patients with Alcohol Use Disorder Undergoing Surgery for Maxillofacial Trauma-A Randomized Pilot Trial.Craniomaxillofacial trauma & reconstruction · 2025Article
- Psychological and Physical Health Outcomes Associated with Gender-Affirming Medical Care for Transgender and Gender-Diverse Youth: A Critical Review.Healthcare (Basel, Switzerland) · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone mass attained early in life is one of the most important determinants of lifelong skeletal health. Bone mineral content increases exponentially during childhood. In fact, 40%-60% of the total adult bone mass is accrued during puberty. By the end of the first 2 decades of life, peak bone mass has been reached. Between ages 20-50, bone mass has plateaued, but it continues to remodel. This is regulated by parathyroid hormone (PTH), vitamin D3, and insulin-like growth factor 1 (IGF-1). After the age of 50, bone mass begins to decrease. The purpose of this paper is to review the importance of maximizing peak bone mass and factors that can modify and maintain peak bone mass. Key Concepts: (1)Peak bone mass is attained by the end of the second decade of life.(2)There are more fractures during peak height velocity in adolescence as the body increases in size but bone mineralization lags behind.(3)The risk of adult osteoporosis starts in childhood.(4)There are modifiable and nonmodifiable risk factors that affect peak bone mass. Level of Evidence: IV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.